| 1 | Cameron ManaryMLB, FBOttumwa | 752 | 188.0 | 10.90 | 69 | 86 | 13 | 1 | 4 |
| 2 | Owen DrapeauxRB, MLBLiberty (North Liberty) | 741 | 92.6 | 5.53 | 134 | 25 | 12 | 1 | 8 |
| 3 | Ishara KaloleroSS, RBJefferson (Cedar Rapids) | 736 | 92.0 | 6.63 | 111 | 71 | 9 | 1 | 8 |
| 4 | Koby ChanthalavanhSB, CBOttumwa | 728 | 182.0 | 14.28 | 51 | 75 | 7 | 2 | 4 |
| 5 | Entienne HigginsQBLincoln (Council Bluffs) | 627 | 78.4 | 7.04 | 89 | 30 | 12 | 0 | 8 |
| 6 | Andre RogersRB, LBLincoln (Council Bluffs) | 569 | 71.1 | 5.58 | 102 | 18 | 9 | 0 | 8 |
| 7 | Sutton KollerSB, SSLiberty (North Liberty) | 409 | 51.1 | 7.30 | 56 | 61 | 7 | 0 | 8 |
| 8 | Drew ThompsonRBSPHS (Pleasant Hill) | 382 | 42.4 | 5.88 | 65 | 47 | 6 | 0 | 9 |
| 9 | Seth ReilandRBMuscatine | 362 | 120.7 | 7.39 | 49 | 47 | 2 | 0 | 3 |
| 10 | Dawson KahlRBIowa City | 315 | 105.0 | 7.33 | 43 | 41 | 8 | 0 | 3 |
| 11 | Reece RettigLiberty (North Liberty) | 290 | 32.2 | 4.46 | 65 | 19 | 4 | 1 | 9 |
| 12 | Landon Vander werffSPHS (Pleasant Hill) | 287 | 35.9 | 4.28 | 67 | 54 | 4 | 0 | 8 |
| 13 | Holden HansenQBSPHS (Pleasant Hill) | 284 | 31.6 | 5.26 | 54 | 22 | 7 | 1 | 9 |
| 14 | Jake MeierRB, CBMuscatine | 280 | 93.3 | 7.00 | 40 | 52 | 2 | 2 | 3 |
| 15 | Dallas MillerWR, FSLiberty (North Liberty) | 190 | 21.1 | 10.56 | 18 | 61 | 0 | 0 | 9 |
| 16 | Gabe EgelandRB, MLBIowa City | 165 | 41.2 | 4.58 | 36 | 11 | 1 | 0 | 4 |
| 17 | Dominic SalibiSB, SSIowa City | 156 | 31.2 | 5.38 | 29 | 10 | 1 | 0 | 5 |
| 18 | Brody BeaverRB, OLBLiberty (North Liberty) | 144 | 36.0 | 6.00 | 24 | 40 | 1 | 0 | 4 |
| 19 | Uweza KaloleroRBJefferson (Cedar Rapids) | 106 | 11.8 | 2.94 | 36 | 13 | 0 | 0 | 9 |
| 20 | Charles RobertsRB, SBLiberty (North Liberty) | 101 | 16.8 | 5.61 | 18 | 32 | 2 | 0 | 6 |
| 21 | Matt MitchellQBOttumwa | 100 | 25.0 | 4.17 | 24 | 22 | 5 | 2 | 4 |
| 22 | Brady WattsRB, DBLincoln (Council Bluffs) | 90 | 10.0 | 4.09 | 22 | 0 | 0 | 0 | 9 |
| 23 | Gaven WadeRB, OLBMuscatine | 83 | 27.7 | 3.61 | 23 | 15 | 2 | 0 | 3 |
| 24 | Brannon FlatteryRB, MLBOttumwa | 70 | 17.5 | 7.00 | 10 | 20 | 0 | 0 | 4 |
| 25 | Cael HansenWR, LBLincoln (Council Bluffs) | 61 | 6.8 | 3.05 | 20 | 2 | 3 | 0 | 9 |
| 26 | Stanley CooperRBSPHS (Pleasant Hill) | 60 | 15.0 | 3.53 | 17 | 12 | 0 | 0 | 4 |
| 27 | Efren HuertaCB, RBOttumwa | 52 | 13.0 | 10.40 | 5 | 32 | 1 | 0 | 4 |
| 28 | Tyler SchausFS, RBOttumwa | 50 | 16.7 | 16.67 | 3 | 23 | 1 | 0 | 3 |
| 29 | Dawins CharlesRB, CBJefferson (Cedar Rapids) | 35 | 5.0 | 4.38 | 8 | 18 | 1 | 0 | 7 |
| 30 | Justin OckenfelsFB, OLBOttumwa | 35 | 11.7 | 3.50 | 10 | 8 | 0 | 1 | 3 |
| 31 | Nolan HellerRB, MLBOttumwa | 35 | 8.8 | 2.50 | 14 | 7 | 1 | 0 | 4 |
| 32 | Grant HugheyTE, DLLincoln (Council Bluffs) | 29 | 3.2 | 14.50 | 2 | 0 | 0 | 0 | 9 |
| 33 | Keaton StrandeRB, LBLincoln (Council Bluffs) | 24 | 4.0 | 4.00 | 6 | 0 | 0 | 0 | 6 |
| 34 | Gaige CurtisQBMuscatine | 24 | 8.0 | 2.40 | 10 | 10 | 2 | 0 | 3 |
| 35 | Collin DeckerWR, SSLiberty (North Liberty) | 23 | 3.8 | 23.00 | 1 | 23 | 0 | 0 | 6 |
| 36 | Lloydson Nyenow jrWR, FSJefferson (Cedar Rapids) | 19 | 2.7 | 9.50 | 2 | 8 | 0 | 0 | 7 |
| 37 | Colin GlynnRB, CBMuscatine | 19 | 6.3 | 6.33 | 3 | 9 | 0 | 0 | 3 |
| 38 | Carter SmookRB, LBLincoln (Council Bluffs) | 12 | 3.0 | 4.00 | 3 | 0 | 0 | 0 | 4 |
| 39 | Isaiah LusajoWR, LBLincoln (Council Bluffs) | 11 | 1.2 | 11.00 | 1 | 0 | 0 | 0 | 9 |
| 40 | Jermaine RobinsonWR, CBJefferson (Cedar Rapids) | 10 | 1.1 | 2.50 | 4 | 4 | 0 | 0 | 9 |
| 41 | Sam ZelenovichWRSPHS (Pleasant Hill) | 8 | 1.3 | 4.00 | 2 | 6 | 0 | 0 | 6 |
| 42 | Aiden SandbotheWR, DBLincoln (Council Bluffs) | 7 | 0.8 | 7.00 | 1 | 0 | 0 | 0 | 9 |
| 43 | Tyree TurnerWR, FSJefferson (Cedar Rapids) | 7 | 2.3 | 7.00 | 1 | 0 | 0 | 1 | 3 |
| 44 | Anthony SnodeyDE, TJefferson (Cedar Rapids) | 7 | 0.9 | 2.33 | 3 | 4 | 0 | 0 | 8 |
| 45 | Bobby BaconQBIowa City | 6 | 2.0 | 3.00 | 2 | 6 | 0 | 0 | 3 |
| 46 | Vernon BendaQBJefferson (Cedar Rapids) | 6 | 0.7 | 0.16 | 37 | 31 | 4 | 2 | 9 |
| 47 | Christopher LeeQB, DBLincoln (Council Bluffs) | 5 | 0.6 | 0.71 | 7 | 0 | 0 | 0 | 8 |
| 48 | Zayne RamlWR, CBSCNHS (Sioux City) | 4 | 1.3 | 1.00 | 4 | 5 | 0 | 0 | 3 |
| 49 | Kaden HillsSPHS (Pleasant Hill) | 2 | 0.2 | 2.00 | 1 | 2 | 0 | 0 | 9 |
| 50 | Parker DerbySB, OLBOttumwa | 1 | 0.2 | 1.00 | 1 | 1 | 0 | 0 | 4 |