| 1 | Jaz Greenwood ERA (Brighton) | 24 | 141 | 5.9 | 91 | 1.55 | 67 | 2.10 |
| 2 | Karen AlvarezArrupe Jesuit (Denver) | 19 | 106 | 5.6 | 98 | 1.08 | 44 | 2.41 |
| 3 | Odicei OkraKennedy (Denver) | 23 | 119 | 5.2 | 124 | 0.96 | 71 | 1.68 |
| 4 | Amaya PaulGDSST: Cedar (Denver) | 24 | 124 | 5.2 | 116 | 1.07 | 65 | 1.91 |
| 5 | Jordan MartinezSG, PGElizabeth | 23 | 115 | 5.0 | 114 | 1.01 | 13 | 8.85 |
| 6 | Alaina BonacquistaPG, SGTCA (Colorado Springs) | 24 | 112 | 4.7 | 94 | 1.19 | 33 | 3.39 |
| 7 | Marely GomezPG, SGFort Lupton | 22 | 102 | 4.6 | 107 | 0.95 | 24 | 4.25 |
| 8 | Julia HodellSGHoly Family (Broomfield) | 27 | 125 | 4.6 | 28 | 4.46 | 0 | 0 |
| 9 | Keilani Venegas alvarezSG, PGKennedy (Denver) | 23 | 105 | 4.6 | 125 | 0.84 | 38 | 2.76 |
| 10 | Zaylee Chavez PGFort Lupton | 20 | 91 | 4.6 | 83 | 1.10 | 14 | 6.50 |
| 11 | Katelyn FortuneGDSST: Cedar (Denver) | 23 | 100 | 4.3 | 90 | 1.11 | 39 | 2.56 |
| 12 | Emma NgewasiG, WArvada | 21 | 86 | 4.1 | 44 | 1.96 | 48 | 1.79 |
| 13 | Mena TuckerMoffat County (Craig) | 23 | 93 | 4.0 | 84 | 1.11 | 26 | 3.58 |
| 14 | Peyton MarvelSGD'Evelyn (Denver) | 26 | 104 | 4.0 | 63 | 1.65 | 0 | 104.00 |
| 15 | Kylie HuffDelta | 22 | 88 | 4.0 | 54 | 1.63 | 6 | 14.67 |
| 16 | Essynce ContrerazPG, SGHoly Family (Broomfield) | 27 | 107 | 4.0 | 61 | 1.75 | 0 | 0 |
| 17 | Rylin ChichiricoPG, GJA (Broomfield) | 23 | 90 | 3.9 | 105 | 0.86 | 23 | 3.91 |
| 18 | Ingrid DallaD'Evelyn (Denver) | 26 | 100 | 3.8 | 86 | 1.16 | 0 | 100.00 |
| 19 | Kenya RodriguezSG, SFSummit (Frisco) | 24 | 92 | 3.8 | 106 | 0.87 | 37 | 2.49 |
| 20 | Alex MayColorado Academy (Denver) | 24 | 85 | 3.5 | 41 | 2.07 | 34 | 2.50 |
| 21 | Carmen MedinaWArvada | 21 | 74 | 3.5 | 56 | 1.32 | 39 | 1.90 |
| 22 | Breezy HuffDelta | 24 | 84 | 3.5 | 63 | 1.33 | 8 | 10.50 |
| 23 | Carole TamburinoERA (Brighton) | 24 | 84 | 3.5 | 75 | 1.12 | 82 | 1.02 |
| 24 | Kelsey PetersonSG, PGTCA (Colorado Springs) | 25 | 87 | 3.5 | 65 | 1.34 | 33 | 2.64 |
| 25 | Caroline PhillipsKent Denver (Englewood) | 25 | 86 | 3.4 | 74 | 1.16 | 44 | 1.96 |
| 26 | Aubree HansonSGMiddle Park (Granby) | 21 | 72 | 3.4 | 109 | 0.66 | 41 | 1.76 |
| 27 | Brooklynn CharloPG, PGRRHS (Thornton) | 27 | 92 | 3.4 | 98 | 0.94 | 58 | 1.59 |
| 28 | Shetara RoebuckPG, SGSierra (Colorado Springs) | 19 | 64 | 3.4 | 96 | 0.67 | 50 | 1.28 |
| 29 | Elsa NygrenF, SFJA (Broomfield) | 24 | 80 | 3.3 | 89 | 0.90 | 61 | 1.31 |
| 30 | Skylar MayColorado Academy (Denver) | 24 | 80 | 3.3 | 36 | 2.22 | 40 | 2.00 |
| 31 | Anya PeperSGKent Denver (Englewood) | 25 | 83 | 3.3 | 69 | 1.20 | 45 | 1.84 |
| 32 | Allizzey MadrigalPG, SGUniversity (Greeley) | 26 | 86 | 3.3 | 62 | 1.39 | 57 | 1.51 |
| 33 | Raniya PaulGDSST: Cedar (Denver) | 24 | 79 | 3.3 | 80 | 0.99 | 61 | 1.30 |
| 34 | Olivia KleinPGRCHS (Loveland) | 27 | 88 | 3.3 | 79 | 1.11 | 45 | 1.96 |
| 35 | Berkley SchneiderLutheran (Parker) | 24 | 78 | 3.2 | 0 | 0 | 0 | 0 |
| 36 | Daniella AvilesSGFort Lupton | 18 | 58 | 3.2 | 68 | 0.85 | 11 | 5.27 |
| 37 | Rylyn RomeroSGThe Academy (Westminster) | 23 | 74 | 3.2 | 101 | 0.73 | 70 | 1.06 |
| 38 | Brihanna CrittendonF, GRRHS (Thornton) | 28 | 89 | 3.2 | 82 | 1.08 | 61 | 1.46 |
| 39 | Taylor ToncheSterling | 24 | 76 | 3.2 | 137 | 0.56 | 64 | 1.19 |
| 40 | Karsyn ShahanGPagosa Springs | 26 | 82 | 3.2 | 75 | 1.09 | 66 | 1.24 |
| 41 | Jaliyah MoraPG, SGEnglewood | 21 | 66 | 3.1 | 110 | 0.60 | 61 | 1.08 |
| 42 | Maddie BeverlySGFort Lupton | 21 | 65 | 3.1 | 98 | 0.66 | 16 | 4.06 |
| 43 | Jerrica ThompsonPG, SGTCA (Colorado Springs) | 18 | 55 | 3.1 | 42 | 1.31 | 20 | 2.75 |
| 44 | Alex HarknessSF, SGEnglewood | 20 | 60 | 3.0 | 79 | 0.76 | 36 | 1.67 |
| 45 | Tatum MilenskiLamar | 24 | 69 | 2.9 | 0 | 0 | 0 | 0 |
| 46 | Marisa ReyesGSierra (Colorado Springs) | 19 | 54 | 2.8 | 118 | 0.46 | 32 | 1.69 |
| 47 | Anna JohnsonSGColorado Academy (Denver) | 25 | 71 | 2.8 | 43 | 1.65 | 28 | 2.54 |
| 48 | Madi DiLorenzoERA (Brighton) | 24 | 68 | 2.8 | 69 | 0.99 | 73 | 0.93 |
| 49 | Naomi WolffColorado Academy (Denver) | 24 | 68 | 2.8 | 51 | 1.33 | 17 | 4.00 |
| 50 | Naveah FloresG, PGAWCPA (Aurora) | 17 | 48 | 2.8 | 72 | 0.67 | 13 | 3.69 |
