There were 9 games for Mississippi Region 5A basketball on Tue, 12/21/2021. The featured games were by Mississippi Region 5A top ranked teams Caledonia (MS) @ #2 New Hope (Columbus, MS), Mercer County (Harrodsburg, KY) vs. #5 Saltillo (MS), and Clinton (MS) @ #8 Forest Hill (Jackson, MS). The first game, Port Gibson (MS) @ Natchez (MS), started at 12p.