| 1 | Trent PearmanQBDaniel (Central) | 3769 | 269.2 | 291 | 389 | 0.748 | 45 | 5 | 138 | 14 |
| 2 | Drew SettleQB, SSChapman (Inman) | 3689 | 335.4 | 249 | 380 | 0.655 | 38 | 9 | 121 | 11 |
| 3 | Dylan RamirezQB, FSBroome (Spartanburg) | 3396 | 308.7 | 230 | 365 | 0.630 | 28 | 13 | 104 | 11 |
| 4 | Tanner StatonQB, SBBrookland-Cayce (Cayce) | 1872 | 208.0 | 133 | 205 | 0.649 | 16 | 8 | 104 | 9 |
| 5 | Gavin OwensQBWren (Piedmont) | 1863 | 186.3 | 136 | 246 | 0.553 | 14 | 13 | 77 | 10 |
| 6 | Hernandez O'neal jr.QBKeenan (Columbia) | 1576 | 197.0 | 106 | 168 | 0.631 | 14 | 6 | 107 | 8 |
| 7 | Tripp WilliamsQBPSHS (Charleston) | 1570 | 120.8 | 100 | 207 | 0.483 | 22 | 7 | 95 | 13 |
| 8 | Robert AdamsLower Richland (Hopkins) | 1570 | 157.0 | 79 | 155 | 0.510 | 16 | 7 | 102 | 10 |
| 9 | Ragen DavenportWR, RBPalmetto (Williamston) | 1310 | 145.6 | 107 | 193 | 0.554 | 12 | 11 | 74 | 9 |
| 10 | Colby Shirey QBOCA (Mt. Pleasant) | 1289 | 117.2 | 103 | 155 | 0.665 | 13 | 5 | 107 | 11 |
| 11 | Grayson WhiteDE, QBCamden | 1248 | 89.1 | 108 | 170 | 0.635 | 6 | 6 | 83 | 14 |
| 12 | Javion MartinQB, FSCrestwood (Sumter) | 1242 | 177.4 | 73 | 133 | 0.549 | 12 | 5 | 101 | 7 |
| 13 | Tanner StatonQB, SBBrookland-Cayce (Cayce) | 1195 | 239.0 | 83 | 125 | 0.664 | 8 | 4 | 105 | 5 |
| 14 | Zan DunhamQBChester | 1153 | 128.1 | 92 | 171 | 0.538 | 13 | 5 | 88 | 9 |
| 15 | Aj PendletonFS, QBBHPHS (Honea Path) | 1140 | 103.6 | 68 | 143 | 0.476 | 11 | 10 | 71 | 11 |
| 16 | Stephon GadsdenQB, WRFCHS (Winnsboro) | 988 | 123.5 | 62 | 130 | 0.477 | 7 | 3 | 82 | 8 |
| 17 | Johnny Jones-tuckerQB, WRSouthside (Greenville) | 758 | 84.2 | 75 | 128 | 0.586 | 5 | 2 | 82 | 9 |
| 18 | Whitt MillerQBStrom Thurmond (Johnston) | 725 | 90.6 | 51 | 85 | 0.600 | 4 | 8 | 64 | 8 |
| 19 | Camron GambrellQB, OLBSouthside (Greenville) | 709 | 118.2 | 37 | 53 | 0.698 | 6 | 1 | 142 | 6 |
| 20 | Landon MosleySeneca | 696 | 174.0 | 48 | 90 | 0.533 | 12 | 2 | 109 | 4 |
| 21 | Jeremiah Judd, jr.QBBlue Ridge (Greer) | 587 | 97.8 | 49 | 85 | 0.576 | 6 | 3 | 88 | 6 |
| 22 | Jasean BowensQB, DBCA (Greenville) | 517 | 86.2 | 55 | 87 | 0.632 | 2 | 6 | 58 | 6 |
| 23 | William HyattQBAMHS (North Charleston) | 499 | 124.8 | 33 | 71 | 0.465 | 4 | 4 | 65 | 4 |
| 24 | Trey HorneQBWren (Piedmont) | 443 | 40.3 | 36 | 81 | 0.444 | 3 | 2 | 64 | 11 |
| 25 | Amazay RobinsonQB, OLBBerea (Greenville) | 429 | 85.8 | 38 | 59 | 0.644 | 3 | 4 | 75 | 5 |
| 26 | Jackson GrahamQB, OLBLoris | 362 | 36.2 | 40 | 81 | 0.494 | 2 | 2 | 60 | 10 |
| 27 | Nigel JohnsonQBCrestwood (Sumter) | 304 | 33.8 | 27 | 45 | 0.600 | 4 | 1 | 101 | 9 |
| 28 | Trooper FloydQBChester | 281 | 28.1 | 23 | 43 | 0.535 | 1 | 1 | 72 | 10 |
| 29 | Blaine SimonsQBDaniel (Central) | 263 | 21.9 | 20 | 29 | 0.690 | 4 | 0 | 137 | 12 |
| 30 | Roman BrownQB, DEBerea (Greenville) | 261 | 65.2 | 13 | 28 | 0.464 | 4 | 2 | 89 | 4 |
| 31 | Hunter WoodardQBCA (Greenville) | 257 | 36.7 | 32 | 78 | 0.410 | 0 | 7 | 13 | 7 |
| 32 | Katrez BraceyWR, QBCamden | 206 | 15.8 | 18 | 30 | 0.600 | 0 | 0 | 81 | 13 |
| 33 | Connor RothQBLoris | 173 | 21.6 | 15 | 39 | 0.385 | 2 | 2 | 48 | 8 |
| 34 | Jackson HuffQBLoris | 162 | 27.0 | 18 | 45 | 0.400 | 4 | 4 | 43 | 6 |
| 35 | Ralphael Isaiah hillQBPalmetto (Williamston) | 149 | 16.6 | 16 | 48 | 0.333 | 1 | 9 | 10 | 9 |
| 36 | Braeden EnloeWR, MLBBlue Ridge (Greer) | 139 | 23.2 | 11 | 21 | 0.524 | 2 | 0 | 105 | 6 |
| 37 | Davis BeckleyQBCamden | 118 | 19.7 | 13 | 18 | 0.722 | 3 | 0 | 129 | 6 |
| 38 | Coleman GrayQBChapman (Inman) | 86 | 21.5 | 8 | 10 | 0.800 | 2 | 0 | 144 | 4 |
| 39 | Antonio "t-hop" hopkins jrLB, RBChester | 86 | 6.6 | 2 | 2 | 1.000 | 0 | 0 | 138 | 13 |
| 40 | Malachi ReyesFS, QBWren (Piedmont) | 51 | 4.6 | 2 | 4 | 0.500 | 0 | 0 | 96 | 11 |
| 41 | Peyton Burton ATHPalmetto (Williamston) | 48 | 5.3 | 8 | 15 | 0.533 | 0 | 1 | 32 | 9 |
| 42 | Tavien OrellanaQB, CBPSHS (Charleston) | 41 | 5.1 | 6 | 6 | 1.000 | 0 | 0 | 114 | 8 |
| 43 | Mekhi JermanQBKeenan (Columbia) | 41 | 10.2 | 3 | 13 | 0.231 | 0 | 1 | 8 | 4 |
| 44 | Anthony Lyles Jr.WR, RBCamden | 40 | 2.9 | 1 | 1 | 1.000 | 0 | 0 | 138 | 14 |
| 45 | Ja'Quan CarterChester | 38 | 3.8 | 2 | 4 | 0.500 | 0 | 0 | 83 | 10 |
| 46 | Tate BrownQBAMHS (North Charleston) | 23 | 5.8 | 3 | 4 | 0.750 | 0 | 1 | 49 | 4 |
| 47 | Mcclain StoklosaAMHS (North Charleston) | 22 | 5.5 | 1 | 1 | 1.000 | 0 | 0 | 138 | 4 |
| 48 | Javius BurtonQB, CBCA (Greenville) | 21 | 2.3 | 3 | 11 | 0.273 | 0 | 2 | 0 | 9 |
| 49 | Brodey ConnDB, PDaniel (Central) | 7 | 0.5 | 1 | 1 | 1.000 | 0 | 0 | 115 | 14 |
| 50 | Drew TaylorBHPHS (Honea Path) | 6 | 1.2 | 1 | 4 | 0.250 | 0 | 0 | 40 | 5 |
