There were 21 games for South Carolina Class AAAAA football on Fri, 10/22/2021. The featured games were by South Carolina Class AAAAA top ranked teams #1 Gaffney (SC) @ #17 Clover (SC), #11 Lexington (SC) @ #2 Dutch Fork (Irmo, SC), and #21 West Ashley (Charleston, SC) @ #4 Fort Dorchester (North Charleston, SC). The first game, Boiling Springs (Spartanburg, SC) @ Fort Mill (SC), started at 7p.