| 1 | Drake RensingRB, OLBMater Dei (Breese) | 915 | 101.7 | 6.78 | 135 | 0 | 12 | 0 | 9 |
| 2 | Jerry RichardsonRBCollinsville | 794 | 79.4 | 6.51 | 122 | 77 | 9 | 2 | 10 |
| 3 | Brenton LyonsRB, OLBNokomis | 764 | 84.9 | 5.92 | 129 | 85 | 8 | 0 | 9 |
| 4 | Ethan BagwellQB, MLBCollinsville | 575 | 57.5 | 4.71 | 122 | 33 | 9 | 0 | 10 |
| 5 | JD McPhersonOHPHS (CO-OP) (Oblong) | 534 | 59.3 | 5.74 | 93 | 0 | 6 | 0 | 9 |
| 6 | Steven MooreTB, OLBMadison | 464 | 58.0 | 9.28 | 50 | 71 | 8 | 3 | 8 |
| 7 | Trenton ZeebQBMater Dei (Breese) | 445 | 63.6 | 5.12 | 87 | 0 | 3 | 5 | 7 |
| 8 | Zaylon SiskRB, DBNokomis | 441 | 55.1 | 6.78 | 65 | 28 | 7 | 0 | 8 |
| 9 | Craig BertolinoMLBNokomis | 400 | 80.0 | 5.13 | 78 | 21 | 4 | 0 | 5 |
| 10 | Kolby AndersonFS, WRCollinsville | 398 | 36.2 | 6.12 | 65 | 38 | 9 | 0 | 11 |
| 11 | KJ DavisOHPHS (CO-OP) (Oblong) | 394 | 43.8 | 6.68 | 59 | 0 | 6 | 0 | 9 |
| 12 | Brandon ThackerOHPHS (CO-OP) (Oblong) | 362 | 40.2 | 5.48 | 66 | 0 | 3 | 0 | 9 |
| 13 | Jaylene WilliamsTB, ILBMadison | 269 | 33.6 | 5.60 | 48 | 51 | 4 | 1 | 8 |
| 14 | Daryl EvansRB, DLNokomis | 267 | 33.4 | 5.04 | 53 | 18 | 2 | 0 | 8 |
| 15 | Carlis WilsonATH, FSMadison | 259 | 32.4 | 6.82 | 38 | 55 | 5 | 0 | 8 |
| 16 | Derrion EnlowQB, CBMadison | 250 | 35.7 | 11.90 | 21 | 60 | 2 | 3 | 7 |
| 17 | Nolan HerpstreithRB, DBNokomis | 231 | 25.7 | 5.37 | 43 | 21 | 4 | 0 | 9 |
| 18 | Isaiah NortonMLB, RBCollinsville | 138 | 12.5 | 8.62 | 16 | 32 | 1 | 0 | 11 |
| 19 | Carl HarrisRB, DBGranite City | 128 | 21.3 | 5.12 | 25 | 22 | 3 | 0 | 6 |
| 20 | Jamarkus LoftonRBCHA (Chicago) | 124 | 41.3 | 6.20 | 20 | 20 | 1 | 0 | 3 |
| 21 | Brock RevermannRB, OLBMater Dei (Breese) | 103 | 11.4 | 5.72 | 18 | 0 | 2 | 0 | 9 |
| 22 | Kendrick LyonsQB, DBGranite City | 100 | 16.7 | 3.33 | 30 | 30 | 0 | 0 | 6 |
| 23 | Nicki RobertsOHPHS (CO-OP) (Oblong) | 80 | 10.0 | 7.27 | 11 | 0 | 1 | 0 | 8 |
| 24 | Kameron TrammelWR, CBMadison | 65 | 8.1 | 9.29 | 7 | 18 | 1 | 0 | 8 |
| 25 | Rollin ArmesMLBCollinsville | 59 | 5.9 | 5.36 | 11 | 13 | 3 | 0 | 10 |
| 26 | Jamari WestCB, WRCHA (Chicago) | 52 | 17.3 | 7.43 | 7 | 26 | 0 | 0 | 3 |
| 27 | Ryan QuinnRB, DBNokomis | 50 | 12.5 | 6.25 | 8 | 11 | 2 | 0 | 4 |
| 28 | Chase ReynoldsQBCollinsville | 47 | 5.2 | 9.40 | 5 | 18 | 0 | 0 | 9 |
| 29 | Kaylon BurseyWR, CBMadison | 44 | 14.7 | 4.40 | 10 | 22 | 0 | 0 | 3 |
| 30 | Ian PostonWR, DBGranite City | 44 | 6.3 | 2.75 | 16 | 10 | 0 | 0 | 7 |
| 31 | Brody SteeleQBNokomis | 40 | 4.4 | 2.00 | 20 | 11 | 0 | 0 | 9 |
| 32 | Chase JansenQB, SSMater Dei (Breese) | 38 | 4.2 | 3.17 | 12 | 0 | 0 | 0 | 9 |
| 33 | Jaeveon HiltonMLB, QBCHA (Chicago) | 34 | 11.3 | 2.43 | 14 | 17 | 2 | 0 | 3 |
| 34 | Reeve DennisOHPHS (CO-OP) (Oblong) | 30 | 3.3 | 1.88 | 16 | 0 | 1 | 0 | 9 |
| 35 | Jcoryn LandryHB, DBGranite City | 26 | 3.7 | 1.53 | 17 | 6 | 0 | 0 | 7 |
| 36 | Ryan McintyreWRCollinsville | 24 | 4.0 | 8.00 | 3 | 22 | 0 | 2 | 6 |
| 37 | Isaiah WilliamsWB, OLBMadison | 23 | 2.9 | 11.50 | 2 | 0 | 0 | 0 | 8 |
| 38 | Sincere CollinsWB, OLBMadison | 22 | 2.8 | 22.00 | 1 | 0 | 0 | 0 | 8 |
| 39 | Kerwin BakerWR, LBMadison | 22 | 3.7 | 11.00 | 2 | 20 | 0 | 0 | 6 |
| 40 | Eddie Jenkins jrQB, CBCHA (Chicago) | 22 | 7.3 | 1.83 | 12 | 13 | 3 | 0 | 3 |
| 41 | Christian SmithCollinsville | 17 | 1.7 | 8.50 | 2 | 14 | 0 | 0 | 10 |
| 42 | Aaron GreenSSCHA (Chicago) | 16 | 5.3 | 16.00 | 1 | 16 | 0 | 0 | 3 |
| 43 | Amari Rodgers-parottDB, HBGranite City | 16 | 3.2 | 3.20 | 5 | 9 | 1 | 0 | 5 |
| 44 | Michael TongayRBCollinsville | 14 | 2.0 | 3.50 | 4 | 5 | 0 | 0 | 7 |
| 45 | Gabe SchlimmeRB, SSMater Dei (Breese) | 12 | 1.3 | 4.00 | 3 | 0 | 0 | 0 | 9 |
| 46 | Marquese BerryLB, DBGranite City | 11 | 1.6 | 5.50 | 2 | 8 | 0 | 0 | 7 |
| 47 | Dalton MarkusSS, TEMater Dei (Breese) | 11 | 1.2 | 2.75 | 4 | 0 | 0 | 0 | 9 |
| 48 | Nick LampeWR, CBMater Dei (Breese) | 4 | 0.5 | 1.33 | 3 | 0 | 0 | 0 | 8 |
| 49 | Eric StuberCollinsville | 3 | 0.3 | 3.00 | 1 | 3 | 0 | 0 | 11 |
| 50 | Mondray CrumeCollinsville | 3 | 0.3 | 3.00 | 1 | 3 | 1 | 0 | 9 |
