| 1 | Darren PennellQB, CBCollinsville | 2850 | 259.1 | 2158 | 692 | 0 | 11 |
| 2 | Jayden EllingtonQBACHS (Belleville) | 2166 | 180.5 | 1584 | 582 | 0 | 12 |
| 3 | Trenton ZeebQB, DBMater Dei (Breese) | 1993 | 166.1 | 1549 | 444 | 0 | 12 |
| 4 | Dierre Hill jrRB, FSACHS (Belleville) | 1967 | 178.8 | 16 | 1788 | 163 | 11 |
| 5 | Jaccarion JonesSt. Teresa (Decatur) | 1510 | 188.8 | 0 | 1472 | 38 | 8 |
| 6 | Aj StrongRB, OLBACHS (Belleville) | 1119 | 93.2 | 0 | 973 | 146 | 12 |
| 7 | Charleston ColdonWR, CBACHS (Belleville) | 903 | 75.2 | 0 | 33 | 870 | 12 |
| 8 | Chase ReynoldsWR, CBCollinsville | 804 | 73.1 | 147 | 238 | 419 | 11 |
| 9 | Khalil Thorps-wattWR, FSCollinsville | 755 | 75.5 | 0 | 30 | 725 | 10 |
| 10 | Ryan McintyreWR, CBCollinsville | 726 | 66.0 | 0 | 436 | 290 | 11 |
| 11 | Amari Rodgers-parottWR, CBCollinsville | 590 | 59.0 | 0 | 0 | 590 | 10 |
| 12 | Garrick WinkelerTE, LBMater Dei (Breese) | 553 | 50.3 | 0 | 19 | 534 | 11 |
| 13 | Brandon ThackerRB, LBOHPHS (CO-OP) (Oblong) | 545 | 68.1 | 0 | 533 | 12 | 8 |
| 14 | Markus KehrerTE, DEMater Dei (Breese) | 436 | 43.6 | 0 | 322 | 114 | 10 |
| 15 | Max SchilawskiQB, SSSt. Teresa (Decatur) | 427 | 53.4 | 459 | -32 | 0 | 8 |
| 16 | Judah SweitzerQB, DBOHPHS (CO-OP) (Oblong) | 390 | 43.3 | 407 | -17 | 0 | 9 |
| 17 | Brock RevermannnRB, LBMater Dei (Breese) | 332 | 33.2 | 0 | 233 | 99 | 10 |
| 18 | Steven BrownRB, FSACHS (Belleville) | 288 | 32.0 | 0 | 200 | 88 | 9 |
| 19 | Deacon HagenRB, DLMater Dei (Breese) | 269 | 24.5 | 0 | 259 | 10 | 11 |
| 20 | Monty SnyderSt. Teresa (Decatur) | 258 | 28.7 | 0 | 169 | 89 | 9 |
| 21 | Bryson OliverSt. Teresa (Decatur) | 253 | 28.1 | 0 | 212 | 41 | 9 |
| 22 | Caiden KernaghanQB, SSSt. Teresa (Decatur) | 220 | 31.4 | 0 | 129 | 91 | 7 |
| 23 | Nick LampeWR, DBMater Dei (Breese) | 216 | 24.0 | 0 | -5 | 221 | 9 |
| 24 | Elliott RakersWR, DBMater Dei (Breese) | 202 | 25.2 | 0 | 0 | 202 | 8 |
| 25 | Ray WoodwardRB, DBOHPHS (CO-OP) (Oblong) | 192 | 24.0 | 0 | 38 | 154 | 8 |
| 26 | Isaiah GordonWR, CBCollinsville | 185 | 18.5 | 0 | 0 | 185 | 10 |
| 27 | Carter MurphyWR, DBMater Dei (Breese) | 163 | 13.6 | 0 | 0 | 163 | 12 |
| 28 | Kylin JordanCB, WRACHS (Belleville) | 161 | 17.9 | 0 | 0 | 161 | 9 |
| 29 | Isaiah NortonMLB, RBCollinsville | 152 | 13.8 | 0 | 153 | -1 | 11 |
| 30 | Peyton PittengerTE, DLOHPHS (CO-OP) (Oblong) | 138 | 15.3 | 0 | 0 | 138 | 9 |
| 31 | Carson MusgraveRB, LBOHPHS (CO-OP) (Oblong) | 111 | 15.9 | 0 | 51 | 60 | 7 |
| 32 | Cooper ZimmerDE, DTACHS (Belleville) | 106 | 8.8 | 0 | 0 | 106 | 12 |
| 33 | Landon GrapperhausWR, DBMater Dei (Breese) | 104 | 8.7 | 0 | 50 | 54 | 12 |
| 34 | Chase ZurlieneQB, LBMater Dei (Breese) | 100 | 25.0 | 80 | 20 | 0 | 4 |
| 35 | Gabe SchlemmeRB, DBMater Dei (Breese) | 90 | 9.0 | 0 | 55 | 35 | 10 |
| 36 | Beckett WadeWR, DBMater Dei (Breese) | 85 | 9.4 | 0 | 0 | 85 | 9 |
| 37 | RJ HaysWR, DBOHPHS (CO-OP) (Oblong) | 82 | 9.1 | 0 | -4 | 86 | 9 |
| 38 | Mark PokrzywinskiSt. Teresa (Decatur) | 77 | 11.0 | 0 | 27 | 50 | 7 |
| 39 | Owen PottsQB, LBOHPHS (CO-OP) (Oblong) | 69 | 7.7 | 100 | -31 | 0 | 9 |
| 40 | Devin HabermehlDE, TECollinsville | 63 | 5.7 | 0 | 0 | 63 | 11 |
| 41 | Chase JansenQB, LBMater Dei (Breese) | 62 | 5.2 | 43 | 13 | 6 | 12 |
| 42 | Brett HilmesWR, DBMater Dei (Breese) | 55 | 7.9 | 0 | 45 | 10 | 7 |
| 43 | Matthew ReynoldsWRCollinsville | 38 | 4.2 | 0 | -1 | 39 | 9 |
| 44 | Lucas JacquotRB, LBACHS (Belleville) | 36 | 6.0 | 0 | 36 | 0 | 6 |
| 45 | Caden GoodwinWR, LBOHPHS (CO-OP) (Oblong) | 35 | 3.9 | 0 | 0 | 35 | 9 |
| 46 | Jackson ChapmanRBSt. Teresa (Decatur) | 28 | 4.0 | 9 | 0 | 19 | 7 |
| 47 | Jale'k NelsonCBCollinsville | 27 | 3.4 | 0 | 0 | 27 | 8 |
| 48 | Johnathan HilmesOL, LBMater Dei (Breese) | 23 | 2.6 | 0 | 0 | 23 | 9 |
| 49 | Wyatt GoldenTE, MLBACHS (Belleville) | 22 | 1.8 | 0 | 0 | 22 | 12 |
| 50 | Lucas BlessingRB, DBOHPHS (CO-OP) (Oblong) | 15 | 1.7 | 0 | 0 | 15 | 9 |
