| 1 | Dane VanceQBNorth Mac (Virden) | 2015 | 223.9 | 1645 | 364 | 6 | 9 |
| 2 | Blake RimbeyQB, FSSouthwestern (Piasa) | 1692 | 169.2 | 1199 | 493 | 0 | 10 |
| 3 | Wyatt KileQBPana | 1646 | 164.6 | 1211 | 435 | 0 | 10 |
| 4 | Tate DobrinichQB, DBLitchfield/Mt. Olive | 1535 | 170.6 | 1468 | 67 | 0 | 9 |
| 5 | AJ SypherdRB, LBLitchfield/Mt. Olive | 1398 | 155.3 | 0 | 1388 | 10 | 9 |
| 6 | Rex ReelsQB, DBCarlinville | 1326 | 132.6 | 1180 | 146 | 0 | 10 |
| 7 | Tristen WargoQBGillespie | 1300 | 144.4 | 1175 | 125 | 0 | 9 |
| 8 | Dalton BiancoQB, DBSBHHS (CO-OP) (Staunton) | 930 | 103.3 | 752 | 178 | 0 | 9 |
| 9 | Isaiah HarbertPana | 850 | 94.4 | 0 | 845 | 5 | 9 |
| 10 | Zander WellsWR, CBHillsboro | 847 | 94.1 | 15 | 664 | 168 | 9 |
| 11 | Hunter NewellWR, CBSouthwestern (Piasa) | 691 | 69.1 | 0 | 288 | 403 | 10 |
| 12 | James GravesNorth Mac (Virden) | 686 | 76.2 | 0 | 564 | 122 | 9 |
| 13 | Mason GilpinWR, DBCarlinville | 627 | 62.7 | 0 | 342 | 285 | 10 |
| 14 | Logan GriffithRB, OLBGillespie | 624 | 69.3 | 0 | 523 | 101 | 9 |
| 15 | Rocky DarrWR, LBSouthwestern (Piasa) | 599 | 66.6 | 0 | 458 | 141 | 9 |
| 16 | Collin GriffithRB, OLBGillespie | 590 | 65.6 | 0 | 123 | 467 | 9 |
| 17 | Braden BuffingtonWR, DBSBHHS (CO-OP) (Staunton) | 588 | 65.3 | 12 | 70 | 506 | 9 |
| 18 | Payne McleanNorth Mac (Virden) | 581 | 64.6 | 6 | 132 | 443 | 9 |
| 19 | Dylan LessmanRB, CBHillsboro | 571 | 81.6 | 0 | 537 | 34 | 7 |
| 20 | Logan KeithTE, DESouthwestern (Piasa) | 562 | 56.2 | 0 | 325 | 237 | 10 |
| 21 | Jack RouseRB, DBCarlinville | 558 | 93.0 | 0 | 492 | 66 | 6 |
| 22 | Drake RoseFB, DLSBHHS (CO-OP) (Staunton) | 509 | 56.6 | 0 | 395 | 114 | 9 |
| 23 | Carson SaathoffTE, LBLitchfield/Mt. Olive | 509 | 56.6 | 0 | 0 | 509 | 9 |
| 24 | Nick LancasterWR, OLBNorth Mac (Virden) | 503 | 55.9 | 0 | 0 | 503 | 9 |
| 25 | Nate DyerRB, DBCarlinville | 470 | 47.0 | 0 | 429 | 41 | 10 |
| 26 | Trace TretteneroRB, DBSBHHS (CO-OP) (Staunton) | 464 | 51.6 | 0 | 435 | 29 | 9 |
| 27 | Sam SimsWR, DBPana | 420 | 42.0 | 0 | 229 | 191 | 10 |
| 28 | Martavious JonesWR, DBLitchfield/Mt. Olive | 414 | 46.0 | 0 | 0 | 414 | 9 |
| 29 | Dawson MorganRB, SSGillespie | 409 | 45.4 | 0 | 91 | 318 | 9 |
| 30 | Jace StewartRBHillsboro | 398 | 56.9 | 256 | 121 | 21 | 7 |
| 31 | Cade McreadyNorth Mac (Virden) | 387 | 43.0 | 0 | 17 | 370 | 9 |
| 32 | Treyton KuhlRBHillsboro | 386 | 42.9 | 0 | 386 | 0 | 9 |
| 33 | Cash LynchWR, CBPana | 346 | 38.4 | 0 | 12 | 334 | 9 |
| 34 | Cole FileDB, WRPana | 342 | 38.0 | 0 | 0 | 342 | 9 |
| 35 | Ian BrantleyWR, LBSouthwestern (Piasa) | 339 | 33.9 | 0 | 0 | 339 | 10 |
| 36 | Triston ThompsonWR, DBCarlinville | 282 | 28.2 | 0 | 5 | 277 | 10 |
| 37 | Drake McsperrittRB, MLBHillsboro | 272 | 30.2 | 0 | 272 | 0 | 9 |
| 38 | Keenan PowellWR, DBLitchfield/Mt. Olive | 233 | 25.9 | 0 | 0 | 233 | 9 |
| 39 | Easton GrammerWR, DBLitchfield/Mt. Olive | 205 | 22.8 | 0 | 0 | 205 | 9 |
| 40 | Jamarion CobbinsC, RBPana | 199 | 39.8 | 22 | 56 | 121 | 5 |
| 41 | Weston KuykendallOG, DLCarlinville | 177 | 17.7 | 0 | 177 | 0 | 10 |
| 42 | Jesse BerryFS, WRGillespie | 172 | 19.1 | 0 | 0 | 172 | 9 |
| 43 | Noah ByotsWR, LBCarlinville | 168 | 16.8 | 0 | 22 | 146 | 10 |
| 44 | Noah ConveryTE, DECarlinville | 163 | 18.1 | 0 | 0 | 163 | 9 |
| 45 | Zach ChapmanWR, DBCarlinville | 133 | 19.0 | 0 | 0 | 133 | 7 |
| 46 | Cayden DurbinRB, OLBPana | 127 | 15.9 | 0 | 127 | 0 | 8 |
| 47 | Dawson LancasterWR, OLBGillespie | 125 | 13.9 | 0 | 9 | 116 | 9 |
| 48 | Tyler RenchTE, OLBPana | 123 | 12.3 | 0 | 0 | 123 | 10 |
| 49 | Brody ShawQBGillespie | 118 | 16.9 | 28 | 90 | 0 | 7 |
| 50 | Chase KnetzerHillsboro | 117 | 14.6 | 43 | 6 | 68 | 8 |
