| 1 | John PetersonRB, OLBVancleave | 2616 | 218.0 | 7.15 | 366 | 94 | 34 | 5 | 12 |
| 2 | Dante DowdellRB, DEPicayune | 2165 | 166.5 | 8.42 | 257 | 98 | 31 | 4 | 13 |
| 3 | Mehki GaddisRBNCHS (Philadelphia) | 1700 | 141.7 | 5.76 | 295 | 0 | 13 | 0 | 12 |
| 4 | Jayden ReedRBLafayette (Oxford) | 1589 | 132.4 | 5.58 | 285 | 54 | 27 | 1 | 12 |
| 5 | Grey BradleyFSEast Central (Moss Point) | 1125 | 102.3 | 6.32 | 178 | 72 | 10 | 2 | 11 |
| 6 | Chris DavisPicayune | 1078 | 71.9 | 8.84 | 122 | 39 | 15 | 0 | 15 |
| 7 | Eli SmithRBEast Central (Moss Point) | 1008 | 168.0 | 8.20 | 123 | 67 | 12 | 1 | 6 |
| 8 | Curdarrious BulluckRB, OLBLake Cormorant | 847 | 77.0 | 5.33 | 159 | 35 | 13 | 0 | 11 |
| 9 | Traylon MinorQB, WRNatchez | 800 | 80.0 | 7.02 | 114 | 64 | 10 | 1 | 10 |
| 10 | Adam TolliverRBJim Hill (Jackson) | 746 | 74.6 | 4.49 | 166 | 45 | 5 | 1 | 10 |
| 11 | Xzavion QuickRB, LBFlorence | 739 | 73.9 | 7.70 | 96 | 80 | 7 | 1 | 10 |
| 12 | Trey HarrisRB, OLBWest Harrison (Gulfport) | 703 | 87.9 | 8.17 | 86 | 78 | 8 | 0 | 8 |
| 13 | Marvin MooreRBCallaway (Jackson) | 646 | 53.8 | 5.72 | 113 | 0 | 6 | 0 | 12 |
| 14 | Darrell SmithPicayune | 641 | 45.8 | 13.35 | 48 | 57 | 9 | 9 | 14 |
| 15 | Jeremy JonesRBWest Harrison (Gulfport) | 567 | 70.9 | 5.73 | 99 | 27 | 11 | 0 | 8 |
| 16 | Javon MccalebbRBWest Harrison (Gulfport) | 552 | 69.0 | 8.90 | 62 | 74 | 7 | 2 | 8 |
| 17 | Octavious PernellQB, FSHCCHS (Lexington) | 537 | 53.7 | 6.80 | 79 | 0 | 11 | 0 | 10 |
| 18 | Quay ThompsonCB, SCallaway (Jackson) | 533 | 44.4 | 8.46 | 63 | 0 | 6 | 0 | 12 |
| 19 | Marquavion CuffRBRidgeland | 515 | 51.5 | 5.42 | 95 | 19 | 6 | 0 | 10 |
| 20 | Kedarius WadeQB, WRCallaway (Jackson) | 514 | 42.8 | 7.91 | 65 | 0 | 13 | 0 | 12 |
| 21 | Deuce KnightQBGeorge County (Lucedale) | 488 | 54.2 | 8.41 | 58 | 80 | 12 | 2 | 9 |
| 22 | Hunter ParkerVancleave | 484 | 40.3 | 5.15 | 94 | 62 | 8 | 1 | 12 |
| 23 | Charles Stevenson jrNCHS (Philadelphia) | 479 | 39.9 | 9.04 | 53 | 0 | 2 | 0 | 12 |
| 24 | Darnell SmithPicayune | 473 | 36.4 | 6.57 | 72 | 0 | 6 | 2 | 13 |
| 25 | Kaden IrvingQBGautier | 462 | 35.5 | 5.19 | 89 | 60 | 17 | 3 | 13 |
| 26 | Marcus CunninghamRBGautier | 433 | 39.4 | 6.01 | 72 | 41 | 4 | 1 | 11 |
| 27 | Andrew MarbleRBEast Central (Moss Point) | 418 | 38.0 | 5.65 | 74 | 57 | 8 | 2 | 11 |
| 28 | Jontavous ShoemateRBProvine (Jackson) | 418 | 52.2 | 4.98 | 84 | 40 | 4 | 0 | 8 |
| 29 | Kaleb BoggansCB, WRFlorence | 414 | 59.1 | 12.54 | 33 | 70 | 9 | 0 | 7 |
| 30 | Ben MyrickRBEast Central (Moss Point) | 401 | 66.8 | 9.33 | 43 | 54 | 5 | 1 | 6 |
| 31 | Keannan PalmerQB, WRHCCHS (Lexington) | 386 | 42.9 | 5.01 | 77 | 0 | 2 | 1 | 9 |
| 32 | Clevaris DixonRB, LBHCCHS (Lexington) | 363 | 45.4 | 5.58 | 65 | 0 | 3 | 0 | 8 |
| 33 | Derius WilliamsRB, WRJim Hill (Jackson) | 347 | 38.6 | 7.54 | 46 | 62 | 4 | 2 | 9 |
| 34 | Jordan StapletonRBWest Harrison (Gulfport) | 341 | 68.2 | 11.00 | 31 | 76 | 1 | 0 | 5 |
| 35 | Ja'braxton BooneWR, RBRidgeland | 317 | 39.6 | 4.95 | 64 | 15 | 5 | 0 | 8 |
| 36 | Carl Mcdonald jrRB, WRNatchez | 310 | 31.0 | 5.44 | 57 | 48 | 2 | 0 | 10 |
| 37 | Ka'mari PayneRBRidgeland | 304 | 60.8 | 6.08 | 50 | 29 | 2 | 0 | 5 |
| 38 | Bj BelleloMLB, TEPRCHS (Carriere) | 275 | 27.5 | 4.58 | 60 | 0 | 3 | 0 | 10 |
| 39 | Gavin HowardATHHCCHS (Lexington) | 271 | 30.1 | 10.84 | 25 | 0 | 1 | 0 | 9 |
| 40 | Garrison DavisQBRidgeland | 261 | 23.7 | 3.90 | 67 | 15 | 8 | 0 | 11 |
| 41 | Richard WareRBProvine (Jackson) | 260 | 43.3 | 5.65 | 46 | 20 | 3 | 1 | 6 |
| 42 | Kantrell Thomas JrQBCallaway (Jackson) | 260 | 21.7 | 4.64 | 56 | 0 | 2 | 0 | 12 |
| 43 | Baker WalkerQBLake Cormorant | 259 | 28.8 | 2.94 | 88 | 38 | 1 | 4 | 9 |
| 44 | Emmitt HighSBGautier | 255 | 23.2 | 6.71 | 38 | 46 | 1 | 0 | 11 |
| 45 | Jacobe StreetRB, OLBGeorge County (Lucedale) | 238 | 29.8 | 3.61 | 66 | 18 | 6 | 2 | 8 |
| 46 | Matthew MicheleFS, RBPRCHS (Carriere) | 234 | 33.4 | 3.49 | 67 | 12 | 2 | 1 | 7 |
| 47 | Marquavius EvansCBProvine (Jackson) | 209 | 34.8 | 3.67 | 57 | 18 | 2 | 0 | 6 |
| 48 | Qorday RussellQBPRCHS (Carriere) | 203 | 25.4 | 3.50 | 58 | 5 | 0 | 0 | 8 |
| 49 | Monterio LillyQB, OLBJim Hill (Jackson) | 194 | 21.6 | 2.40 | 81 | 12 | 1 | 1 | 9 |
| 50 | Elijah RuffinSS, WRNCHS (Philadelphia) | 189 | 15.8 | 4.50 | 42 | 0 | 10 | 0 | 12 |
