| 1 | Zach GullungRBHancock (Kiln) | 1530 | 127.5 | 6.51 | 235 | 80 | 18 | 0 | 12 |
| 2 | Michael JohnsonSouth Panola (Batesville) | 1379 | 106.1 | 7.18 | 192 | 62 | 22 | 1 | 13 |
| 3 | Mykel AllenSS, WRSouth Panola (Batesville) | 1209 | 93.0 | 6.72 | 180 | 80 | 17 | 0 | 13 |
| 4 | Marvin MooreRB, DBCallaway (Jackson) | 1152 | 128.0 | 11.52 | 100 | 0 | 9 | 0 | 9 |
| 5 | Adam TolliverRBJim Hill (Jackson) | 1098 | 109.8 | 5.06 | 217 | 35 | 12 | 0 | 10 |
| 6 | Darrell SmithPicayune | 1087 | 98.8 | 8.77 | 124 | 0 | 15 | 6 | 11 |
| 7 | Mekhi GaddisRBNCHS (Philadelphia) | 1075 | 97.7 | 6.14 | 175 | 43 | 7 | 1 | 11 |
| 8 | Trey HarrisRB, OLBWest Harrison (Gulfport) | 1045 | 104.5 | 7.68 | 136 | 0 | 0 | 0 | 10 |
| 9 | Niquis RatcliffPicayune | 1000 | 76.9 | 8.85 | 113 | 0 | 17 | 2 | 13 |
| 10 | Chris DavisPicayune | 944 | 134.9 | 7.15 | 132 | 0 | 11 | 4 | 7 |
| 11 | Jordan StapletonRBWest Harrison (Gulfport) | 926 | 132.3 | 11.29 | 82 | 0 | 0 | 0 | 7 |
| 12 | Jacobe StreetRB, OLBGeorge County (Lucedale) | 852 | 71.0 | 5.60 | 152 | 52 | 9 | 4 | 12 |
| 13 | Decorey Knight jrRB, ATHVicksburg | 818 | 74.4 | 8.52 | 96 | 0 | 4 | 0 | 11 |
| 14 | Eric Collins jr.RBWCHS (Vicksburg) | 790 | 65.8 | 5.06 | 156 | 76 | 13 | 4 | 12 |
| 15 | Jarcoby HopsonSSLake Cormorant | 785 | 78.5 | 5.38 | 146 | 93 | 8 | 5 | 10 |
| 16 | Qorday RussellQB, RBPRCHS (Carriere) | 720 | 80.0 | 5.62 | 128 | 9 | 4 | 4 | 9 |
| 17 | Kylan RhodesRB, OLBOlive Branch | 654 | 130.8 | 7.11 | 92 | 79 | 8 | 0 | 5 |
| 18 | Duran McClendonRB, DBCallaway (Jackson) | 649 | 59.0 | 7.13 | 91 | 0 | 1 | 1 | 11 |
| 19 | Jeremy JonesRBWest Harrison (Gulfport) | 637 | 63.7 | 5.31 | 120 | 0 | 0 | 0 | 10 |
| 20 | Brandon GautierRBGeorge County (Lucedale) | 631 | 52.6 | 6.07 | 104 | 75 | 2 | 3 | 12 |
| 21 | Joshaun WilliamsRBLake Cormorant | 619 | 61.9 | 5.48 | 113 | 77 | 4 | 2 | 10 |
| 22 | Ashton Fair (k1)QB, TETerry | 509 | 42.4 | 6.13 | 83 | 47 | 4 | 0 | 12 |
| 23 | Jerry Wall IIIOLB, RBOlive Branch | 489 | 48.9 | 5.04 | 97 | 53 | 5 | 0 | 10 |
| 24 | Malik MontgomeryRB, OLBVicksburg | 465 | 51.7 | 5.47 | 85 | 0 | 6 | 0 | 9 |
| 25 | Chrishawn WoodcoxRBCallaway (Jackson) | 453 | 64.7 | 10.30 | 44 | 0 | 4 | 2 | 7 |
| 26 | Cedrick BlackmoreRB, FBVicksburg | 439 | 43.9 | 6.55 | 67 | 0 | 3 | 0 | 10 |
| 27 | Jordan MageeQB, OLBTerry | 428 | 38.9 | 8.39 | 51 | 55 | 3 | 0 | 11 |
| 28 | Aden GreerRB, LBWCHS (Vicksburg) | 388 | 32.3 | 4.91 | 79 | 36 | 4 | 1 | 12 |
| 29 | Jeffrey HopgoodMLB, RBHancock (Kiln) | 382 | 31.8 | 8.13 | 47 | 19 | 4 | 0 | 12 |
| 30 | Ronde BakerRBTerry | 354 | 39.3 | 6.56 | 54 | 39 | 2 | 1 | 9 |
| 31 | Deuce KnightQBGeorge County (Lucedale) | 340 | 48.6 | 5.31 | 64 | 76 | 8 | 4 | 7 |
| 32 | Ronnie leroy AlexanderQBVicksburg | 321 | 32.1 | 6.83 | 47 | 0 | 1 | 3 | 10 |
| 33 | Jeremiah ConteeFBPicayune | 321 | 24.7 | 5.02 | 64 | 0 | 3 | 0 | 13 |
| 34 | Marcus ChristonWR, CBSouth Panola (Batesville) | 272 | 22.7 | 6.80 | 40 | 32 | 2 | 2 | 12 |
| 35 | Kejuan WilliamsRB, OLBLake Cormorant | 267 | 33.4 | 5.93 | 45 | 44 | 2 | 1 | 8 |
| 36 | Jakevion JonesRB, OLBTerry | 265 | 22.1 | 7.57 | 35 | 23 | 2 | 1 | 12 |
| 37 | Mark KirklandRBNCHS (Philadelphia) | 260 | 37.1 | 4.56 | 57 | 15 | 1 | 0 | 7 |
| 38 | Javon MccalebbRBWest Harrison (Gulfport) | 245 | 49.0 | 8.17 | 30 | 0 | 0 | 0 | 5 |
| 39 | Raheem VanceQBOlive Branch | 213 | 23.7 | 3.00 | 71 | 26 | 1 | 0 | 9 |
| 40 | Collin JohnsonVicksburg | 210 | 30.0 | 9.13 | 23 | 0 | 1 | 0 | 7 |
| 41 | Kantrell Thomas JrQBCallaway (Jackson) | 194 | 24.2 | 5.54 | 35 | 0 | 5 | 1 | 8 |
| 42 | Gage ReevesSSGeorge County (Lucedale) | 188 | 15.7 | 5.88 | 32 | 20 | 4 | 0 | 12 |
| 43 | Rj HallFS, WRTerry | 176 | 14.7 | 13.54 | 13 | 35 | 2 | 0 | 12 |
| 44 | Anderrious FlowersMLBSouth Panola (Batesville) | 174 | 13.4 | 5.61 | 31 | 29 | 2 | 0 | 13 |
| 45 | Brenn MoodyWR, CBGeorge County (Lucedale) | 172 | 17.2 | 6.62 | 26 | 82 | 6 | 7 | 10 |
| 46 | Nicholas RodgersWRTerry | 166 | 23.7 | 23.71 | 7 | 25 | 0 | 0 | 7 |
| 47 | Will WilliamsQBNCHS (Philadelphia) | 138 | 12.5 | 3.83 | 36 | 0 | 0 | 1 | 11 |
| 48 | Tyson JohnsonWR, CBWest Harrison (Gulfport) | 130 | 16.2 | 14.44 | 9 | 0 | 0 | 0 | 8 |
| 49 | Zayden ReedWRLake Cormorant | 127 | 14.1 | 5.29 | 24 | 41 | 1 | 0 | 9 |
| 50 | Jadarius YoungDE, OLBTerry | 109 | 13.6 | 8.38 | 13 | 22 | 0 | 0 | 8 |