| 1 | Tyler BakerQBCanisius (Buffalo) | 2450 | 245.0 | 2019 | 431 | 0 | 10 |
| 2 | Christian LewisRB, DLSt. Mary's (Lancaster) | 2148 | 238.7 | 0 | 2141 | 7 | 9 |
| 3 | Steve Otremba jr.QBSt. Francis (Hamburg) | 1389 | 126.3 | 1226 | 163 | 0 | 11 |
| 4 | Ricardo KiddRB, OLBSt. Francis (Hamburg) | 1148 | 104.4 | 0 | 1099 | 49 | 11 |
| 5 | Jayden WilsonQB, FSSt. Mary's (Lancaster) | 1111 | 123.4 | 610 | 501 | 0 | 9 |
| 6 | Jeff PilarskiQB, CBBTSJ (Buffalo) | 903 | 90.3 | 726 | 159 | 18 | 10 |
| 7 | Mike DoctorWR, CBCanisius (Buffalo) | 758 | 75.8 | 0 | 22 | 736 | 10 |
| 8 | Lamar ThomasRB, SSCanisius (Buffalo) | 629 | 62.9 | 0 | 272 | 357 | 10 |
| 9 | Brandon ThreetQB, FSCOHHS (Tonawanda) | 572 | 114.4 | 499 | 73 | 0 | 5 |
| 10 | Aaron JentzQBSJCI (Buffalo) | 512 | 85.3 | 483 | 29 | 0 | 6 |
| 11 | Jarrell GreenWR, CBCOHHS (Tonawanda) | 483 | 80.5 | 169 | 60 | 254 | 6 |
| 12 | Logan ReaskaWR, FSSt. Francis (Hamburg) | 470 | 47.0 | 0 | 0 | 470 | 10 |
| 13 | Josh FillionFS, WRCanisius (Buffalo) | 457 | 45.7 | 0 | 0 | 457 | 10 |
| 14 | Kimal ClarkCB, SSSt. Francis (Hamburg) | 455 | 41.4 | 0 | 190 | 265 | 11 |
| 15 | Cureem HathcockRBCanisius (Buffalo) | 386 | 38.6 | 0 | 367 | 19 | 10 |
| 16 | Jeremy ConnorQB, RBSJCI (Buffalo) | 374 | 46.8 | 195 | 144 | 35 | 8 |
| 17 | Dion AndersonSJCI (Buffalo) | 322 | 40.2 | 0 | 170 | 152 | 8 |
| 18 | Clarence PrudeRBBTSJ (Buffalo) | 312 | 34.7 | 1 | 288 | 23 | 9 |
| 19 | Marcus JohnsonSt. Mary's (Lancaster) | 287 | 31.9 | 0 | 229 | 58 | 9 |
| 20 | Gerald MccloudWR, DBBTSJ (Buffalo) | 282 | 31.3 | 0 | 64 | 218 | 9 |
| 21 | Antonio MorganCB, WRCanisius (Buffalo) | 265 | 29.4 | 0 | 0 | 265 | 9 |
| 22 | Makari InabenettRB, LBBTSJ (Buffalo) | 244 | 34.9 | 42 | 93 | 109 | 7 |
| 23 | Roderick MillerRB, OLBCanisius (Buffalo) | 237 | 23.7 | 0 | 197 | 40 | 10 |
| 24 | Jack BestpitchWR, CBSt. Mary's (Lancaster) | 227 | 25.2 | 5 | 13 | 209 | 9 |
| 25 | Will RahillFB, MLBSJCI (Buffalo) | 216 | 36.0 | 0 | 179 | 37 | 6 |
| 26 | Micheal RossWR, DECOHHS (Tonawanda) | 211 | 35.2 | 0 | 0 | 211 | 6 |
| 27 | Robert AnspachSJCI (Buffalo) | 210 | 26.2 | 0 | -6 | 216 | 8 |
| 28 | Simmarion ThreetRB, CBCOHHS (Tonawanda) | 208 | 34.7 | 0 | 113 | 95 | 6 |
| 29 | Demaris Pettiway-ScarverRB, LBBTSJ (Buffalo) | 190 | 23.8 | 0 | 187 | 3 | 8 |
| 30 | Terrence PendergrassRB, OLBSt. Francis (Hamburg) | 186 | 23.2 | 0 | 144 | 42 | 8 |
| 31 | Alex EllisonWR, CBSt. Mary's (Lancaster) | 160 | 22.9 | 0 | 0 | 160 | 7 |
| 32 | Trevor SheehanWR, LSSt. Mary's (Lancaster) | 155 | 17.2 | 0 | 5 | 150 | 9 |
| 33 | Zaire LeonardRB, CBCanisius (Buffalo) | 147 | 18.4 | 0 | 92 | 55 | 8 |
| 34 | Aaron RoseboroCB, WRSt. Francis (Hamburg) | 143 | 13.0 | 0 | 4 | 139 | 11 |
| 35 | Laron BeaumontWR, DBBTSJ (Buffalo) | 139 | 17.4 | 0 | 22 | 117 | 8 |
| 36 | Chris MeadowsWR, CBBTSJ (Buffalo) | 130 | 13.0 | 0 | 0 | 130 | 10 |
| 37 | Jimmy ScottSt. Francis (Hamburg) | 123 | 12.3 | 0 | 98 | 25 | 10 |
| 38 | Ryan HerseySt. Mary's (Lancaster) | 105 | 11.7 | 0 | 78 | 27 | 9 |
| 39 | Malik WilliamsWR, OLBSt. Francis (Hamburg) | 103 | 12.9 | 0 | 0 | 103 | 8 |
| 40 | Brett PapkeFS, WRCanisius (Buffalo) | 99 | 12.4 | 0 | 0 | 99 | 8 |
| 41 | Eryan LawrenceSt. Francis (Hamburg) | 92 | 23.0 | 0 | 19 | 73 | 4 |
| 42 | Jakson RossRB, MLBCOHHS (Tonawanda) | 92 | 18.4 | 0 | 14 | 78 | 5 |
| 43 | Mike NoonanSJCI (Buffalo) | 81 | 16.2 | 0 | -10 | 91 | 5 |
| 44 | Steve HoskinsSJCI (Buffalo) | 78 | 9.8 | 0 | -6 | 84 | 8 |
| 45 | Darrell HamiltonDT, FBCanisius (Buffalo) | 56 | 7.0 | 0 | 56 | 0 | 8 |
| 46 | Ethan O'haraWR, MLBBTSJ (Buffalo) | 56 | 8.0 | 0 | 0 | 56 | 7 |
| 47 | Kynan Ulanga iiCBSt. Francis (Hamburg) | 35 | 5.8 | 0 | 0 | 35 | 6 |
| 48 | Jayvon NewkirkQB, DBBTSJ (Buffalo) | 33 | 4.1 | 11 | -7 | 29 | 8 |
| 49 | Zane SchenkWRSJCI (Buffalo) | 28 | 9.3 | 0 | 5 | 23 | 3 |
| 50 | Connor MillerRB, OLBSt. Francis (Hamburg) | 23 | 2.3 | 0 | 23 | 0 | 10 |
