| 1 | Thad NofsingerTB, LBWaynedale (Apple Creek) | 2005 | 167.1 | 7.54 | 266 | 0 | 24 | 0 | 12 |
| 2 | John PettigrewRB, LBCVCA (Cuyahoga Falls) | 1948 | 177.1 | 8.74 | 223 | 90 | 18 | 6 | 11 |
| 3 | Blake KnowltonTB, DLWGHS (Waynesfield) | 1722 | 172.2 | 8.08 | 213 | 70 | 19 | 5 | 10 |
| 4 | Marcus WrightFB, LBDunbar (Dayton) | 1690 | 169.0 | 7.19 | 235 | 62 | 21 | 0 | 10 |
| 5 | Taylor HarrisRB, LBHighland (Marengo) | 1661 | 207.6 | 9.66 | 172 | 0 | 29 | 0 | 8 |
| 6 | Jacob LohriRBTyler (Sistersville) | 1658 | 150.7 | 7.15 | 232 | 68 | 19 | 0 | 11 |
| 7 | Mark NicholsRB, DBNewark Catholic (Newark) | 1622 | 202.8 | 8.72 | 186 | 0 | 26 | 0 | 8 |
| 8 | Isaiah PeadRB, DBEA (Columbus) | 1615 | 201.9 | 11.45 | 141 | 0 | 33 | 0 | 8 |
| 9 | Kyle KordichTB, DBNorth Royalton | 1591 | 144.6 | 5.00 | 318 | 39 | 17 | 3 | 11 |
| 10 | Blaine SchmittAllen East (Harrod) | 1547 | 154.7 | 5.07 | 305 | 68 | 13 | 6 | 10 |
| 11 | Brandon BeachumRB, LBCMHS (Youngstown) | 1525 | 117.3 | 6.28 | 243 | 60 | 14 | 4 | 13 |
| 12 | Rodney StewartRB, DBBrookhaven (Columbus) | 1504 | 167.1 | 10.82 | 139 | 0 | 27 | 0 | 9 |
| 13 | Logan KaufmanRB, LBOttawa-Glandorf (Ottawa) | 1469 | 122.4 | 7.00 | 210 | 64 | 15 | 2 | 12 |
| 14 | Josh SlemkerRBEaton | 1467 | 146.7 | 6.04 | 243 | 77 | 0 | 0 | 10 |
| 15 | Sam SmallwoodLB, FBMiami East (Casstown) | 1440 | 130.9 | 6.99 | 206 | 65 | 21 | 15 | 11 |
| 16 | Brandon StephensonRB, LBShawnee (Lima) | 1432 | 143.2 | 6.85 | 209 | 70 | 23 | 2 | 10 |
| 17 | Heath NicklesRB, DBColumbus Grove | 1406 | 140.6 | 6.30 | 223 | 98 | 11 | 3 | 10 |
| 18 | Ryan KnauberRB, LBCLHS (Cardington) | 1399 | 155.4 | 8.85 | 158 | 0 | 20 | 0 | 9 |
| 19 | Josh HertelFB, ILBColumbiana | 1399 | 127.2 | 7.32 | 191 | 86 | 17 | 1 | 11 |
| 20 | Koby FryeRB, DBMemorial (St. Marys) | 1392 | 139.2 | 5.90 | 236 | 63 | 12 | 2 | 10 |
| 21 | Ben MoodyRB, DBLakeview (Cortland) | 1367 | 105.2 | 5.65 | 242 | 69 | 11 | 0 | 13 |
| 22 | Erick HowardRB, LBHoover (North Canton) | 1308 | 109.0 | 4.74 | 276 | 0 | 0 | 0 | 12 |
| 23 | Cameron BrantRB, OLBMapleton (Ashland) | 1303 | 130.3 | 4.97 | 262 | 88 | 10 | 1 | 10 |
| 24 | Wes PiersonRB, DBRock Hill (Ironton) | 1296 | 117.8 | 6.89 | 188 | 0 | 17 | 0 | 11 |
| 25 | Ryan WilliamsQB, FSColumbiana | 1274 | 115.8 | 6.31 | 202 | 59 | 9 | 1 | 11 |
| 26 | Dan McCarthyQB, DBCMHS (Youngstown) | 1219 | 101.6 | 7.92 | 154 | 84 | 15 | 1 | 12 |
| 27 | Seth MillarRB, DBWaynesville | 1216 | 110.5 | 6.91 | 176 | 95 | 17 | 0 | 11 |
| 28 | Gene OnabiyiRB, DBLake (Uniontown) | 1178 | 107.1 | 7.05 | 167 | 65 | 14 | 4 | 11 |
| 29 | Neal SeamanQB, DBLouisville | 1178 | 84.1 | 5.19 | 227 | 0 | 0 | 0 | 14 |
| 30 | Marcus JohnstonHB, OLBCoshocton | 1175 | 106.8 | 7.08 | 166 | 70 | 12 | 0 | 11 |
| 31 | Carlin IslesRBJackson (Massillon) | 1167 | 129.7 | 7.25 | 161 | 0 | 0 | 0 | 9 |
| 32 | Kevin JohnsonTB, CBKRHS (Springfield) | 1166 | 116.6 | 6.10 | 191 | 67 | 7 | 2 | 10 |
| 33 | Tony BrittonQB, DBCrestview (Columbiana) | 1156 | 115.6 | 7.36 | 157 | 80 | 12 | 3 | 10 |
| 34 | Demetrius TrappsRBAyersville (Defiance) | 1146 | 127.3 | 11.58 | 99 | 0 | 17 | 0 | 9 |
| 35 | Dominique SherrerRBColerain (Cincinnati) | 1140 | 103.6 | 6.99 | 163 | 82 | 19 | 1 | 11 |
| 36 | Tyler CrowlRB, DBLake (Uniontown) | 1134 | 103.1 | 7.27 | 156 | 81 | 12 | 2 | 11 |
| 37 | Mike HaddadRB, LBAvon Lake | 1130 | 113.0 | 8.01 | 141 | 80 | 19 | 0 | 10 |
| 38 | Chip KidwellRB, LBBuckeye Valley (Delaware) | 1122 | 112.2 | 7.33 | 153 | 80 | 12 | 2 | 10 |
| 39 | Nathan BrunkRBMVHS (Union City) | 1104 | 110.4 | 6.31 | 175 | 64 | 14 | 4 | 10 |
| 40 | Randy GreenwoodLake Catholic (Mentor) | 1097 | 84.4 | 5.93 | 185 | 90 | 16 | 2 | 13 |
| 41 | Clayton KirbyRBPVHS (Andover) | 1093 | 121.4 | 7.01 | 156 | 0 | 0 | 0 | 9 |
| 42 | Mike CaseRBLockland | 1093 | 109.3 | 5.91 | 185 | 57 | 11 | 0 | 10 |
| 43 | Cortez FlemingQBWSHS (Westerville) | 1081 | 135.1 | 6.36 | 170 | 0 | 15 | 0 | 8 |
| 44 | Max ColanerRB, SSCCCHS (Canton) | 1080 | 90.0 | 6.07 | 178 | 0 | 0 | 0 | 12 |
| 45 | Gavin PainterBath (Lima) | 1077 | 107.7 | 4.85 | 222 | 59 | 4 | 4 | 10 |
| 46 | Steven SpillmanRB, LBTVHS (Zoarville) | 1071 | 97.4 | 5.79 | 185 | 0 | 13 | 0 | 11 |
| 47 | Anthony SmithRB, DBGlenOak (Canton) | 1065 | 118.3 | 5.46 | 195 | 0 | 0 | 0 | 9 |
| 48 | Devoe TorrenceWashington (Massillon) | 1062 | 118.0 | 6.00 | 177 | 0 | 0 | 0 | 9 |
| 49 | Connor PainRB, DBNapoleon | 1045 | 87.1 | 5.25 | 199 | 66 | 11 | 5 | 12 |
| 50 | Jared KendziorskiLB, RBClaymont (Uhrichsville) | 1031 | 103.1 | 5.43 | 190 | 53 | 8 | 3 | 10 |