| 1 | Zackery BlackwellRB, MLBACHS (Martinez) | 2201 | 183.4 | 8.03 | 274 | 73 | 26 | 0 | 12 |
| 2 | Ethan KellyRB, DBFCHS (Florence) | 1501 | 150.1 | 10.14 | 148 | 86 | 19 | 1 | 10 |
| 3 | Matt LaytonQB, FSCA (St. Matthews) | 1308 | 130.8 | 6.35 | 206 | 67 | 15 | 2 | 10 |
| 4 | Loncelle DaleyDE, RBHHP (Hilton Head Island) | 1255 | 114.1 | 5.84 | 215 | 0 | 13 | 0 | 11 |
| 5 | Coleby SinclairPee Dee Academy (Mullins) | 1169 | 106.3 | 8.35 | 140 | 57 | 12 | 3 | 11 |
| 6 | Freeman BarberRBPorter-Gaud (Charleston) | 955 | 106.1 | 6.82 | 140 | 67 | 12 | 0 | 9 |
| 7 | Juels I huntleyWR, DBFCHS (Florence) | 947 | 94.7 | 9.47 | 100 | 90 | 8 | 1 | 10 |
| 8 | Hayden HickmanWR, RBDillon Christian (Dillon) | 946 | 105.1 | 9.75 | 97 | 80 | 11 | 0 | 9 |
| 9 | Anthony jarius “aj” ReyesPCNHS (Columbia) | 945 | 118.1 | 6.18 | 153 | 90 | 7 | 2 | 8 |
| 10 | Anthony FrippRB, MLBTHA (Ridgeland) | 879 | 97.7 | 9.06 | 97 | 0 | 6 | 0 | 9 |
| 11 | Tony O'bannerRB, WRTHA (Ridgeland) | 848 | 84.8 | 7.71 | 110 | 0 | 10 | 0 | 10 |
| 12 | Jamari HarrisQBTSA (Dalzell) | 728 | 80.9 | 6.22 | 117 | 61 | 12 | 1 | 9 |
| 13 | Rondarius PorterDT, RBHHEHS (Columbia) | 712 | 64.7 | 8.48 | 84 | 57 | 8 | 0 | 11 |
| 14 | Shane DareRB, KPP (Summerville) | 662 | 60.2 | 5.61 | 118 | 0 | 7 | 0 | 11 |
| 15 | Kade StricklandATH, DECA (St. Matthews) | 633 | 63.3 | 6.03 | 105 | 62 | 9 | 1 | 10 |
| 16 | Juw-el HuntleyQB, DBFCHS (Florence) | 632 | 57.5 | 6.26 | 101 | 46 | 10 | 4 | 11 |
| 17 | Miles FulghumCB, RBGCHS (Greenwood) | 541 | 90.2 | 5.94 | 91 | 55 | 3 | 0 | 6 |
| 18 | Ayden AllenRB, OLBTSA (Dalzell) | 534 | 59.3 | 6.59 | 81 | 75 | 6 | 1 | 9 |
| 19 | Dylan LesesneRB, OLBHHEHS (Columbia) | 459 | 38.2 | 4.14 | 111 | 68 | 7 | 0 | 12 |
| 20 | Andrew TuckerWB, SSCA (St. Matthews) | 441 | 44.1 | 7.48 | 59 | 58 | 8 | 1 | 10 |
| 21 | Grant ChandlerWR, LBGCHS (Greenwood) | 440 | 48.9 | 5.95 | 74 | 80 | 2 | 0 | 9 |
| 22 | Tate SistareQBWilson Hall (Sumter) | 385 | 38.5 | 3.93 | 98 | 46 | 2 | 0 | 10 |
| 23 | Ryan ShirleyWR, CBGCHS (Greenwood) | 383 | 38.3 | 6.18 | 62 | 60 | 2 | 0 | 10 |
| 24 | Marshall PritchettWR, SSPorter-Gaud (Charleston) | 354 | 39.3 | 5.90 | 60 | 31 | 3 | 1 | 9 |
| 25 | Dallas CarterRB, WRACHS (Martinez) | 352 | 39.1 | 5.50 | 64 | 0 | 5 | 0 | 9 |
| 26 | Landyn TylerOLB, WRPee Dee Academy (Mullins) | 344 | 31.3 | 11.86 | 29 | 57 | 4 | 0 | 11 |
| 27 | Michael BrownRBPorter-Gaud (Charleston) | 317 | 39.6 | 5.28 | 60 | 14 | 3 | 0 | 8 |
| 28 | Adrian OkeeWR, RBBA (Savannah) | 310 | 77.5 | 6.60 | 47 | 55 | 1 | 0 | 4 |
| 29 | Colton TaylorFB, MLBGCHS (Greenwood) | 292 | 29.2 | 4.36 | 67 | 14 | 5 | 0 | 10 |
| 30 | Nicholas RobinsonMLBTHA (Ridgeland) | 271 | 33.9 | 8.21 | 33 | 0 | 3 | 0 | 8 |
| 31 | Ellis ChangQBPorter-Gaud (Charleston) | 260 | 37.1 | 5.31 | 49 | 22 | 2 | 2 | 7 |
| 32 | Tray PeltQB, LBDillon Christian (Dillon) | 259 | 32.4 | 3.87 | 67 | 50 | 3 | 1 | 8 |
| 33 | Dietrich ShufordQB, FSTHA (Ridgeland) | 255 | 63.8 | 10.20 | 25 | 0 | 2 | 0 | 4 |
| 34 | Brandon HowardMLB, OLBTHA (Ridgeland) | 247 | 22.5 | 11.76 | 21 | 0 | 5 | 0 | 11 |
| 35 | James TownsendCB, WRTHA (Ridgeland) | 243 | 22.1 | 11.04 | 22 | 0 | 2 | 0 | 11 |
| 36 | Jerome RicheyWR, CBBA (Savannah) | 239 | 26.6 | 5.69 | 42 | 46 | 4 | 0 | 9 |
| 37 | Lawson PritchettSSPorter-Gaud (Charleston) | 235 | 26.1 | 13.82 | 17 | 28 | 2 | 0 | 9 |
| 38 | Jake Rodney-brown(2)RBHHP (Hilton Head Island) | 226 | 28.2 | 5.80 | 39 | 0 | 4 | 0 | 8 |
| 39 | Quadir ScottQB, DBCA (Myrtle Beach) | 225 | 56.2 | 3.88 | 58 | 30 | 2 | 2 | 4 |
| 40 | Triston RandallMLBBA (Savannah) | 223 | 24.8 | 3.48 | 64 | 29 | 4 | 0 | 9 |
| 41 | Doc WalkerRB, OLBWilson Hall (Sumter) | 222 | 22.2 | 3.36 | 66 | 30 | 6 | 0 | 10 |
| 42 | Luke CarterPee Dee Academy (Mullins) | 221 | 20.1 | 5.97 | 37 | 48 | 5 | 0 | 11 |
| 43 | Dominic BlueRB, LBDillon Christian (Dillon) | 216 | 24.0 | 6.97 | 31 | 68 | 2 | 0 | 9 |
| 44 | Lane NoeOL, DTCA (St. Matthews) | 205 | 20.5 | 15.77 | 13 | 72 | 3 | 1 | 10 |
| 45 | Walker DraffinHHEHS (Columbia) | 205 | 17.1 | 4.18 | 49 | 18 | 5 | 0 | 12 |
| 46 | Donald TomlinQBHHEHS (Columbia) | 201 | 16.8 | 4.57 | 44 | 24 | 0 | 0 | 12 |
| 47 | Justin AnsleyRB, CBHHEHS (Columbia) | 198 | 39.6 | 7.33 | 27 | 92 | 2 | 0 | 5 |
| 48 | Romond RobinsonOL, DLBA (Savannah) | 193 | 21.4 | 5.68 | 34 | 49 | 1 | 0 | 9 |
| 49 | Javion LammieFB, DETSA (Dalzell) | 186 | 26.6 | 5.47 | 34 | 25 | 3 | 0 | 7 |
| 50 | Will CroftWilson Hall (Sumter) | 181 | 22.6 | 3.85 | 47 | 53 | 2 | 0 | 8 |
