| 1 | A'ja WilsonFHHEHS (Columbia) | 25 | 860 | 34.4 | 323 | 473 | 68 | 4 | 25 | 173 | 76 |
| 2 | Amber CampbellGNA (Charleston) | 33 | 1072 | 32.5 | 425 | 648 | 66 | 48 | 38 | 174 | 77 |
| 3 | Jada WallacePGBroome (Spartanburg) | 23 | 744 | 32.3 | 305 | 673 | 45 | 0 | 0 | 134 | 72 |
| 4 | Malia RiversPGCentral (Pageland) | 16 | 459 | 28.7 | 157 | 52 | 0 | 37 | 0 | 108 | 0 |
| 5 | Brittany WilliamsSG, PGKingstree | 29 | 737 | 25.4 | 280 | 367 | 76 | 102 | 72 | 33 | 82 |
| 6 | Miranda WeslakeFBA (Beaufort) | 19 | 457 | 24.1 | 156 | 432 | 36 | 39 | 30 | 85 | 70 |
| 7 | Shaunice FulmoreF, GLake City | 23 | 498 | 21.7 | 211 | 389 | 54 | 7 | 0 | 69 | 69 |
| 8 | Corey CaulderPG, SGPCA (Mt. Pleasant) | 25 | 536 | 21.4 | 198 | 482 | 41 | 42 | 33 | 98 | 72 |
| 9 | Brittani McDonaldGMullins | 17 | 363 | 21.4 | 159 | 349 | 46 | 1 | 3 | 44 | 56 |
| 10 | DaQuasha WilliamsCNinety Six | 22 | 467 | 21.2 | 202 | 380 | 53 | 0 | 0 | 63 | 37 |
| 11 | TaKeria LegettePG, PFLatta | 22 | 467 | 21.2 | 174 | 217 | 80 | 67 | 87 | 52 | 67 |
| 12 | Ta'asia WrightGDenmark-Olar (Denmark) | 22 | 456 | 20.7 | 87 | 0 | 0 | 3 | 0 | 30 | 0 |
| 13 | Cierra CarterFSpring Valley (Columbia) | 25 | 518 | 20.7 | 176 | 336 | 52 | 47 | 43 | 119 | 76 |
| 14 | Sade' EliSG, PFTimmonsville | 26 | 516 | 19.8 | 202 | 416 | 49 | 25 | 32 | 87 | 67 |
| 15 | Asia WrightPG, SGLee Central (Bishopville) | 12 | 233 | 19.4 | 75 | 0 | 0 | 34 | 0 | 49 | 73 |
| 16 | Daisja CannonGBattery Creek (Beaufort) | 26 | 502 | 19.3 | 201 | 352 | 57 | 44 | 47 | 56 | 57 |
| 17 | Khaila WebbPG, SGDorman (Roebuck) | 27 | 514 | 19.0 | 187 | 410 | 46 | 51 | 31 | 89 | 75 |
| 18 | Olivia McDanielG, FLake View | 14 | 266 | 19.0 | 93 | 221 | 42 | 16 | 23 | 64 | 49 |
| 19 | Katie MinichanSABC (Aiken) | 18 | 332 | 18.4 | 133 | 464 | 29 | 14 | 16 | 52 | 51 |
| 20 | Tasia HopkinsPG, GWoodland (Dorchester) | 18 | 331 | 18.4 | 113 | 121 | 93 | 30 | 61 | 75 | 64 |
| 21 | Jaleah LasaneGMullins | 17 | 306 | 18.0 | 119 | 294 | 40 | 28 | 27 | 40 | 53 |
| 22 | Ross MathisGBlue Ridge (Greer) | 24 | 431 | 18.0 | 142 | 407 | 35 | 73 | 0 | 74 | 76 |
| 23 | Ya'shai PauleyGLamar | 26 | 453 | 17.4 | 167 | 569 | 29 | 56 | 23 | 63 | 53 |
| 24 | Desaree GreenF, CCarvers Bay (Hemingway) | 20 | 347 | 17.4 | 139 | 262 | 53 | 0 | 0 | 69 | 62 |
| 25 | Mariana EisonF, PGUnion County (Union) | 24 | 414 | 17.2 | 146 | 243 | 60 | 52 | 0 | 70 | 62 |
| 26 | ShaLeighya SultonGChapin | 26 | 442 | 17.0 | 151 | 432 | 35 | 38 | 22 | 102 | 56 |
| 27 | Dareisha SowellG, PGAndrew Jackson (Kershaw) | 26 | 436 | 16.8 | 143 | 339 | 42 | 18 | 27 | 132 | 76 |
| 28 | Haniyyah HowardG, PA.C. Flora (Columbia) | 26 | 436 | 16.8 | 141 | 377 | 37 | 42 | 43 | 112 | 76 |
| 29 | Dashona MagwoodF, GBaptist Hill (Hollywood) | 21 | 352 | 16.8 | 146 | 341 | 43 | 10 | 22 | 48 | 53 |
| 30 | Sonora DengoklPG, SGLakewood (Sumter) | 23 | 385 | 16.7 | 138 | 352 | 39 | 24 | 39 | 85 | 69 |
| 31 | Khrystal EllisSF, PFSouthside (Greenville) | 16 | 266 | 16.6 | 97 | 211 | 46 | 2 | 17 | 48 | 56 |
| 32 | Nakol FranksSG, PGWren (Piedmont) | 26 | 429 | 16.5 | 136 | 362 | 38 | 62 | 37 | 95 | 79 |
| 33 | Kaydra DuckettPF, PGDreher (Columbia) | 25 | 406 | 16.2 | 138 | 445 | 31 | 25 | 22 | 113 | 61 |
| 34 | Ashanti BrownSilver Bluff (Aiken) | 14 | 226 | 16.1 | 81 | 217 | 37 | 4 | 67 | 39 | 52 |
| 35 | Chelise MormanF, GUnion County (Union) | 24 | 386 | 16.1 | 150 | 223 | 67 | 0 | 0 | 86 | 48 |
| 36 | Courtney RobinsonGBlue Ridge (Greer) | 24 | 385 | 16.0 | 150 | 359 | 42 | 10 | 33 | 75 | 66 |
| 37 | Shan NicholsonG, FEmerald (Greenwood) | 19 | 304 | 16.0 | 62 | 0 | 0 | 25 | 0 | 77 | 0 |
| 38 | Jessica EvansPG, SFLatta | 22 | 351 | 16.0 | 135 | 215 | 63 | 10 | 45 | 71 | 53 |
| 39 | Kayla CronGBMCC (Simpsonville) | 17 | 270 | 15.9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 40 | Jasmine FordGLake View | 14 | 222 | 15.9 | 89 | 236 | 38 | 8 | 29 | 36 | 60 |
| 41 | Justice GeePG, SGTimmonsville | 26 | 410 | 15.8 | 163 | 316 | 52 | 7 | 23 | 77 | 70 |
| 42 | Heylan AndersonFLamar | 26 | 405 | 15.6 | 157 | 376 | 42 | 1 | 8 | 90 | 62 |
| 43 | Deanna HousePG, GDarlington | 14 | 216 | 15.4 | 0 | 0 | 0 | 0 | 0 | 11 | 52 |
| 44 | Jada RichardsonPF, FDarlington | 14 | 216 | 15.4 | 0 | 0 | 0 | 0 | 0 | 13 | 57 |
| 45 | Breelyn BlandingPG, SGBlythewood | 22 | 337 | 15.3 | 112 | 286 | 39 | 42 | 31 | 71 | 74 |
| 46 | Dashanique PetersonC, PFKingstree | 29 | 442 | 15.2 | 159 | 200 | 80 | 0 | 0 | 73 | 89 |
| 47 | Bailee WattsLee Academy (Bishopville) | 18 | 272 | 15.1 | 77 | 245 | 31 | 20 | 25 | 69 | 53 |
| 48 | Kyia HoughGLancaster | 21 | 316 | 15.0 | 100 | 237 | 42 | 19 | 32 | 97 | 75 |
| 49 | Amelia GreenGHammond (Columbia) | 25 | 376 | 15.0 | 41 | 116 | 35 | 8 | 22 | 19 | 59 |
| 50 | Jessica SparksSeneca | 23 | 345 | 15.0 | 121 | 242 | 50 | 40 | 0 | 63 | 76 |