| 1 | Chase ThomasG, FBlythewood | 27 | 16.3 | 145 | 189 | 77 |
| 2 | Alaina NettlesPG, SGCane Bay (Summerville) | 26 | 20.2 | 130 | 226 | 58 |
| 3 | Genesis YoungPF, CSpartanburg | 25 | 13.4 | 104 | 182 | 57 |
| 4 | Jadein HaynesG, WStall (Charleston) | 27 | 17.6 | 101 | 143 | 71 |
| 5 | Sydni AndersonPFWhite Knoll (Lexington) | 25 | 9.0 | 92 | 162 | 57 |
| 6 | Sailor ReardenPG, SGSocastee (Myrtle Beach) | 27 | 15.1 | 90 | 108 | 83 |
| 7 | Yasmine CookPF, SFStratford (Goose Creek) | 30 | 14.2 | 87 | 133 | 0 |
| 8 | Anaya MuhammadPG, SGWoodmont (Piedmont) | 25 | 16.4 | 84 | 112 | 75 |
| 9 | Lauren ThomasSF, PFCane Bay (Summerville) | 27 | 8.9 | 84 | 154 | 55 |
| 10 | Jenna YanityPG, SGLexington | 26 | 10.9 | 83 | 117 | 71 |
| 11 | Dasia FergusonG, SFDorman (Roebuck) | 25 | 13.9 | 82 | 108 | 76 |
| 12 | JaiDah LiebertSpring Valley (Columbia) | 29 | 14.1 | 80 | 112 | 71 |
| 13 | Hillary OffingPF, SFDutch Fork (Irmo) | 24 | 17.8 | 78 | 115 | 68 |
| 14 | Trinity NesbittCWoodmont (Piedmont) | 26 | 11.3 | 78 | 117 | 67 |
| 15 | Hayley HightowerSG, PGBlythewood | 27 | 12.1 | 71 | 134 | 53 |
| 16 | Trinity JonesGMauldin | 28 | 14.9 | 68 | 100 | 68 |
| 17 | Madison EntzmingerSpring Valley (Columbia) | 30 | 6.1 | 68 | 110 | 62 |
| 18 | Emma DaughertyPG, SFSummerville | 22 | 10.7 | 64 | 96 | 67 |
| 19 | Shyrique ParkerGGaffney | 21 | 12.7 | 64 | 106 | 60 |
| 20 | Lindsay GarnerCLexington | 26 | 16.5 | 63 | 102 | 62 |
| 21 | Zie'l RatchfordSpring Valley (Columbia) | 28 | 11.4 | 62 | 108 | 57 |
| 22 | MacKenzie MasseySG, SFSocastee (Myrtle Beach) | 27 | 10.1 | 61 | 98 | 62 |
| 23 | Grace IkenegbuSF, PFT.L. Hanna (Anderson) | 28 | 9.5 | 60 | 101 | 59 |
| 24 | Kam SainvilPG, SGSpartanburg | 25 | 9.4 | 59 | 124 | 0 |
| 25 | Te'ericka DowlingPG, SGJames F. Byrnes (Duncan) | 24 | 15.8 | 57 | 75 | 76 |
| 26 | Sanaa SkinnerFSJHS (Murrells Inlet) | 24 | 6.5 | 55 | 2 | 0 |
| 27 | Molly DaughertySG, SFSummerville | 26 | 11.4 | 54 | 69 | 78 |
| 28 | Amani MccraySG, PGBerkeley (Moncks Corner) | 24 | 7.5 | 54 | 84 | 64 |
| 29 | Lachar LawrenceSG, SFCane Bay (Summerville) | 27 | 7.5 | 53 | 107 | 50 |
| 30 | Alyssa CauseyFWando (Mt. Pleasant) | 24 | 6.6 | 52 | 97 | 54 |
| 31 | Zara LeamonPGMauldin | 25 | 13.0 | 51 | 80 | 64 |
| 32 | Vanessa Borrero GarciaSG, SFWhite Knoll (Lexington) | 25 | 7.4 | 51 | 106 | 48 |
| 33 | Samara LucasFClover | 24 | 8.7 | 50 | 75 | 67 |
| 34 | Madison ThomasCSummerville | 26 | 6.3 | 49 | 73 | 67 |
| 35 | Lauren CroslandSpring Valley (Columbia) | 30 | 9.9 | 49 | 98 | 50 |
| 36 | Karis AlexanderPF, SFClover | 24 | 7.0 | 49 | 102 | 48 |
| 37 | Imari HumphreySpring Valley (Columbia) | 30 | 5.2 | 48 | 76 | 63 |
| 38 | Jaden TuckerSG, PGRiver Bluff (Lexington) | 16 | 11.6 | 48 | 80 | 60 |
| 39 | Khalia HartwellC, PFT.L. Hanna (Anderson) | 28 | 7.0 | 48 | 80 | 60 |
| 40 | Asia ClinkscalesPGT.L. Hanna (Anderson) | 28 | 11.9 | 47 | 82 | 57 |
| 41 | Caitlin BowlingPGJ.L. Mann (Greenville) | 23 | 9.6 | 46 | 92 | 50 |
| 42 | Ta'Liya GriffinC, FStratford (Goose Creek) | 28 | 6.5 | 45 | 89 | 51 |
| 43 | Alyric BucknerGWhite Knoll (Lexington) | 24 | 6.8 | 44 | 103 | 43 |
| 44 | Tamerah WynnSF, PFT.L. Hanna (Anderson) | 22 | 8.0 | 43 | 68 | 63 |
| 45 | Krystian SpratleySG, PGDutch Fork (Irmo) | 24 | 6.6 | 42 | 81 | 52 |
| 46 | Chassidy RookardSG, PGJames F. Byrnes (Duncan) | 24 | 12.2 | 41 | 60 | 68 |
| 47 | Imari RichardsonPF, SFJ.L. Mann (Greenville) | 23 | 11.0 | 41 | 68 | 60 |
| 48 | Tyana PullmanCWoodmont (Piedmont) | 26 | 5.8 | 40 | 61 | 66 |
| 49 | Aaliyah LeeGDutch Fork (Irmo) | 24 | 9.6 | 40 | 73 | 55 |
| 50 | Ciara MustapherSG, PGStratford (Goose Creek) | 29 | 11.1 | 39 | 58 | 67 |
