| 1 | Devin WherryRB, LBSouth Pointe (Rock Hill) | 1370 | 105.4 | 5.71 | 240 | 47 | 12 | 0 | 13 |
| 2 | Rockaris KingRB, STimberland (St. Stephen) | 1253 | 179.0 | 8.19 | 153 | 76 | 15 | 1 | 7 |
| 3 | Clay MacIntoshRB, SSCA (North Charleston) | 1246 | 124.6 | 10.21 | 122 | 71 | 10 | 1 | 10 |
| 4 | Quinton SingletonRB, DBSBHS (Summerton) | 1238 | 103.2 | 5.98 | 207 | 59 | 13 | 0 | 12 |
| 5 | Stephon GilmoreQB, DBSouth Pointe (Rock Hill) | 1145 | 88.1 | 6.98 | 164 | 74 | 14 | 9 | 13 |
| 6 | John WalkerRBLakewood (Sumter) | 1144 | 127.1 | 6.25 | 183 | 50 | 11 | 0 | 9 |
| 7 | Simpson MillerRBChesterfield | 1127 | 140.9 | 7.46 | 151 | 75 | 19 | 0 | 8 |
| 8 | John GardnerRB, DEKing Academy (Batesburg) | 1078 | 89.8 | 7.24 | 149 | 0 | 10 | 1 | 12 |
| 9 | Mustafa GreeneRBIrmo (Columbia) | 1067 | 133.4 | 5.53 | 193 | 0 | 7 | 0 | 8 |
| 10 | Steven SandersWB, LBClover | 1048 | 74.9 | 6.28 | 167 | 53 | 6 | 5 | 14 |
| 11 | Palmer QuincyRB, SSSBHS (Summerton) | 1015 | 92.3 | 8.25 | 123 | 85 | 12 | 0 | 11 |
| 12 | Curtis DavisRB, DBSBHS (Summerton) | 906 | 75.5 | 7.74 | 117 | 76 | 11 | 0 | 12 |
| 13 | Chris DouglasWB, LBClover | 902 | 75.2 | 5.43 | 166 | 52 | 9 | 4 | 12 |
| 14 | Michael HermannQB, WRHHP (Hilton Head Island) | 869 | 62.1 | 6.08 | 143 | 89 | 14 | 0 | 14 |
| 15 | Emmanual HightowerRBBen Lippen (Columbia) | 826 | 82.6 | 8.43 | 98 | 87 | 10 | 2 | 10 |
| 16 | Ricky MooreFB, LBClover | 771 | 55.1 | 5.21 | 148 | 49 | 12 | 1 | 14 |
| 17 | Joey DavisWR, DBHHCA (Hilton Head Island) | 744 | 62.0 | 4.28 | 174 | 63 | 9 | 8 | 12 |
| 18 | Pinckney TavarisTB, DBBattery Creek (Beaufort) | 731 | 91.4 | 4.51 | 162 | 45 | 6 | 1 | 8 |
| 19 | Davis LemonCNHS (Columbia) | 730 | 73.0 | 4.22 | 173 | 45 | 4 | 7 | 10 |
| 20 | Ikaika KapuFB, LBSt. Andrew's (Savannah) | 684 | 68.4 | 5.10 | 134 | 0 | 10 | 0 | 10 |
| 21 | Joshua PrattQB, FSKing Academy (Batesburg) | 671 | 55.9 | 6.39 | 105 | 0 | 11 | 0 | 12 |
| 22 | Leander BarneyIrmo (Columbia) | 645 | 80.6 | 6.86 | 94 | 0 | 9 | 0 | 8 |
| 23 | Richard Van De WaterFBBen Lippen (Columbia) | 635 | 57.7 | 8.47 | 75 | 52 | 8 | 3 | 11 |
| 24 | Tyron DouglasWB, DBClover | 570 | 43.8 | 7.22 | 79 | 78 | 7 | 4 | 13 |
| 25 | Cj WashingtonSeneca | 563 | 140.8 | 8.04 | 70 | 0 | 0 | 0 | 4 |
| 26 | Kyle CarpenterWR, DBKing Academy (Batesburg) | 552 | 46.0 | 8.12 | 68 | 0 | 9 | 0 | 12 |
| 27 | Justin ComeauxQB, DBWest-Oak (Westminster) | 527 | 105.4 | 5.92 | 89 | 0 | 0 | 0 | 5 |
| 28 | Meeshon ThompsonDB, RBWalhalla | 526 | 52.6 | 4.31 | 122 | 0 | 2 | 0 | 10 |
| 29 | Keith PoughFB, ILBSBHS (Summerton) | 523 | 43.6 | 7.69 | 68 | 46 | 7 | 0 | 12 |
| 30 | Phillip OsborneHB, CLugoff-Elgin (Lugoff) | 494 | 61.8 | 6.50 | 76 | 62 | 0 | 0 | 8 |
| 31 | Dylan RosserRB, DBHHP (Hilton Head Island) | 477 | 34.1 | 3.76 | 127 | 50 | 8 | 0 | 14 |
| 32 | Blake FergusonRB, LBCA (North Charleston) | 468 | 46.8 | 6.69 | 70 | 26 | 1 | 0 | 10 |
| 33 | Michael WingardDaniel (Central) | 464 | 92.8 | 5.66 | 82 | 0 | 0 | 0 | 5 |
| 34 | Bryan GrahamFB, MLBAMHS (North Charleston) | 456 | 45.6 | 6.00 | 76 | 41 | 5 | 1 | 10 |
| 35 | Kevin BradleySeneca | 447 | 111.8 | 6.04 | 74 | 0 | 0 | 0 | 4 |
| 36 | Zac LennsRB, LBHHCA (Hilton Head Island) | 435 | 36.2 | 4.10 | 106 | 48 | 5 | 2 | 12 |
| 37 | Rennis BlackSE, DBTimberland (St. Stephen) | 424 | 60.6 | 8.15 | 52 | 39 | 4 | 1 | 7 |
| 38 | Labonta ButlerRBLakewood (Sumter) | 410 | 51.2 | 4.10 | 100 | 21 | 1 | 0 | 8 |
| 39 | Bryant BoydRBLakewood (Sumter) | 397 | 56.7 | 7.64 | 52 | 65 | 2 | 0 | 7 |
| 40 | Chris MingerFB, DTLugoff-Elgin (Lugoff) | 388 | 48.5 | 6.69 | 58 | 73 | 0 | 0 | 8 |
| 41 | Thomas GreenTB, FSSt. Andrew's (Savannah) | 357 | 39.7 | 6.38 | 56 | 0 | 2 | 0 | 9 |
| 42 | Montae MonroeWR, DBClover | 342 | 24.4 | 8.77 | 39 | 37 | 1 | 0 | 14 |
| 43 | Kris GreenWB, CBAMHS (North Charleston) | 338 | 33.8 | 4.76 | 71 | 24 | 1 | 0 | 10 |
| 44 | Jones BrownCNHS (Columbia) | 322 | 32.2 | 2.95 | 109 | 36 | 2 | 6 | 10 |
| 45 | Jereme GreenRBSummerville | 271 | 45.2 | 7.13 | 38 | 47 | 4 | 0 | 6 |
| 46 | Louis WrightRB, DBAMHS (North Charleston) | 270 | 27.0 | 4.29 | 63 | 52 | 2 | 0 | 10 |
| 47 | Christopher LeeRBPendleton | 265 | 66.2 | 4.82 | 55 | 0 | 0 | 0 | 4 |
| 48 | Don TomberlinRB, DBSt. Andrew's (Savannah) | 257 | 25.7 | 5.84 | 44 | 0 | 4 | 0 | 10 |
| 49 | Josh McFaddenRBWest Florence (Florence) | 247 | 61.8 | 4.19 | 59 | 31 | 1 | 1 | 4 |
| 50 | Kevin GlickRB, LBHHP (Hilton Head Island) | 240 | 18.5 | 5.11 | 47 | 22 | 4 | 0 | 13 |