| 1 | Keynnard CampbellQB, FSBible Baptist (Savannah) | 4894 | 406.9 | 3039 | 1844 | 11 | 12 |
| 2 | Shuler BentleyQBJames F. Byrnes (Duncan) | 4687 | 334.8 | 4718 | -31 | 0 | 14 |
| 3 | Mason RudolphQB, PNorthwestern (Rock Hill) | 4465 | 297.7 | 3990 | 475 | 0 | 15 |
| 4 | Deriante JenkinsQB, FSLake Marion (Santee) | 3707 | 308.9 | 3447 | 260 | 0 | 12 |
| 5 | J.T. WatersQB, DBPCA (Mt. Pleasant) | 3236 | 286.9 | 1512 | 1644 | 80 | 11 |
| 6 | Christopher KellahanQB, SWA (Kingstree) | 3082 | 280.2 | 1578 | 1504 | 0 | 11 |
| 7 | Tyler RobersonQB, DBACHS (Martinez) | 3035 | 233.5 | 2018 | 1017 | 0 | 13 |
| 8 | Jauveer HammondQB, DBStrom Thurmond (Johnston) | 2932 | 209.4 | 1674 | 1258 | 0 | 14 |
| 9 | Dalton HelmsQBNation Ford (Fort Mill) | 2774 | 252.2 | 2440 | 334 | 0 | 11 |
| 10 | DeAndre BeltonQB, WRFCHS (Winnsboro) | 2679 | 203.5 | 1487 | 1158 | 34 | 13 |
| 11 | RJ RosemondQB, PCA (Greenville) | 2568 | 256.8 | 2297 | 271 | 0 | 10 |
| 12 | A. C. WhaleyQBRNHS (Columbia) | 2516 | 249.8 | 2213 | 285 | 18 | 10 |
| 13 | Kolby WhitleyQB, DBAndrew Jackson (Kershaw) | 2478 | 225.3 | 2192 | 286 | 0 | 11 |
| 14 | Darvia DuboseQB, PDarlington | 2454 | 245.2 | 1581 | 871 | 2 | 10 |
| 15 | John WalkerQBSCHS (Simpsonville) | 2427 | 220.6 | 2525 | -98 | 0 | 11 |
| 16 | Matthew WilliamsQB, DBBHPHS (Honea Path) | 2358 | 196.5 | 2344 | 14 | 0 | 12 |
| 17 | Jacob ClaryQBWren (Piedmont) | 2274 | 227.4 | 2056 | 218 | 0 | 10 |
| 18 | Caleb LewisQB, LBHHCA (Hilton Head Island) | 2272 | 174.8 | 2270 | 2 | 0 | 13 |
| 19 | Will LloydQBNA (Charleston) | 2248 | 200.5 | 1832 | 374 | 42 | 11 |
| 20 | Hyleck FosterRBGaffney | 2068 | 130.2 | 0 | 1823 | 245 | 14 |
| 21 | Kody WatsonQB, LBCNHS (Columbia) | 2036 | 169.7 | 2144 | -108 | 0 | 12 |
| 22 | Akia BookerWRJames F. Byrnes (Duncan) | 2032 | 34.5 | 73 | 410 | 1549 | 14 |
| 23 | RYLAN WELLSQB, KFort Mill | 1927 | 160.6 | 1390 | 537 | 0 | 12 |
| 24 | Troy HarrisonQB, QBBaptist Hill (Hollywood) | 1903 | 211.4 | 1787 | 116 | 0 | 9 |
| 25 | Korey ThompsonRB, DBBHPHS (Honea Path) | 1870 | 143.0 | 0 | 1716 | 154 | 12 |
| 26 | Shaq DavidsonQBGaffney | 1839 | 99.9 | 901 | 598 | 340 | 15 |
| 27 | Stuart WaltersAMHS (North Charleston) | 1822 | 163.9 | 200 | 1603 | 19 | 11 |
| 28 | Will HunterQBLexington | 1821 | 202.3 | 1711 | 110 | 0 | 9 |
| 29 | Darius HammondRBStrom Thurmond (Johnston) | 1809 | 112.0 | 0 | 1568 | 241 | 14 |
| 30 | Spencer BrothersSeneca | 1796 | 199.6 | 1564 | 232 | 0 | 9 |
| 31 | T'darius GreggATHLee Central (Bishopville) | 1787 | 125.9 | 689 | 822 | 276 | 12 |
| 32 | Charlie WilmotQB, DBHHP (Hilton Head Island) | 1780 | 178.0 | 1572 | 208 | 0 | 10 |
| 33 | Caleb HughesQBGeorgetown | 1778 | 161.6 | 1620 | 158 | 0 | 11 |
| 34 | Thomas BanksRB, DBACHS (Martinez) | 1753 | 110.5 | 0 | 1436 | 317 | 13 |
| 35 | Marion McCurryQBOP (Orangeburg) | 1702 | 154.7 | 1472 | 230 | 0 | 11 |
| 36 | Dantez BennamonQBGoose Creek | 1671 | 128.5 | 1136 | 535 | 0 | 13 |
| 37 | Kylen BinnQBBlythewood | 1651 | 136.2 | 1386 | 248 | 17 | 12 |
| 38 | Tramel TerryWR, RBGoose Creek | 1633 | 70.1 | 0 | 841 | 792 | 12 |
| 39 | Shervas BrownRB, QBEstill | 1631 | 137.1 | 356 | 1152 | 123 | 11 |
| 40 | Craig WilliamsQB, CBBurke (Charleston) | 1572 | 145.7 | 1039 | 418 | 115 | 10 |
| 41 | Dorian RainesSeneca | 1547 | 13.4 | 92 | 42 | 1413 | 10 |
| 42 | Xavier AdamsQBMCHS (Bennettsville) | 1527 | 169.7 | 1401 | 126 | 0 | 9 |
| 43 | Grayson KingQBNorth Central (Kershaw) | 1523 | 167.4 | 1493 | 14 | 16 | 9 |
| 44 | Damian BellRB, SFCHS (Winnsboro) | 1519 | 95.5 | 61 | 1180 | 278 | 13 |
| 45 | Dupree HartRBNorthwestern (Rock Hill) | 1515 | 22.3 | 0 | 335 | 1180 | 15 |
| 46 | Marquis ArnoldSeneca | 1502 | 130.7 | 60 | 1247 | 195 | 10 |
| 47 | Mike WilliamsWR, FSLake Marion (Santee) | 1490 | 8.6 | 0 | 95 | 1395 | 11 |
| 48 | Dionte EvansRB, DBCross | 1471 | 77.9 | 25 | 1066 | 380 | 14 |
| 49 | Deo'vonte DoeRB, DBRSAOE (Ridgeland) | 1442 | 125.4 | 0 | 1379 | 63 | 11 |
| 50 | Sawyer BridgesQBSummerville | 1428 | 119.0 | 1354 | 74 | 0 | 12 |
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