| 1 | Shakur ChisolmRB, FSWEHS (Williston) | 2187 | 198.8 | 10.46 | 209 | 0 | 29 | 0 | 11 |
| 2 | Quintyn ReederRB, CBSCHS (Simpsonville) | 2080 | 148.6 | 10.72 | 194 | 91 | 26 | 0 | 14 |
| 3 | Janarick ReedRB, DBMarion | 1973 | 151.8 | 6.90 | 286 | 89 | 26 | 0 | 13 |
| 4 | Rudy MitchellRBWestwood (Blythewood) | 1953 | 150.2 | 9.04 | 216 | 92 | 23 | 4 | 13 |
| 5 | Brandon SinclairRBMyrtle Beach | 1820 | 140.0 | 6.69 | 272 | 61 | 28 | 2 | 13 |
| 6 | Josh SamuelRB, SSJ.L. Mann (Greenville) | 1816 | 165.1 | 7.44 | 244 | 75 | 1 | 0 | 11 |
| 7 | Trevon PrayRB, CBBA (Savannah) | 1793 | 163.0 | 12.54 | 143 | 83 | 23 | 0 | 11 |
| 8 | Kartilus McfaddenRB, OLBLatta | 1663 | 138.6 | 6.99 | 238 | 45 | 14 | 0 | 12 |
| 9 | Shanard BainRB, KRDorman (Roebuck) | 1621 | 108.1 | 5.16 | 314 | 50 | 20 | 1 | 15 |
| 10 | Jerry HowardRBNorthwestern (Rock Hill) | 1570 | 104.7 | 7.89 | 199 | 95 | 19 | 1 | 15 |
| 11 | Isiah OdomMLB, RBCEMHS (Greeleyville) | 1563 | 111.6 | 5.92 | 264 | 55 | 21 | 5 | 14 |
| 12 | Nate SchlosserAMHS (North Charleston) | 1497 | 136.1 | 6.16 | 243 | 45 | 27 | 0 | 11 |
| 13 | Buss HamiltonRB, OLBJames Island (Charleston) | 1485 | 135.0 | 6.54 | 227 | 85 | 21 | 0 | 11 |
| 14 | Teshaun LaneRB, CBDillon Christian (Dillon) | 1484 | 123.7 | 12.06 | 123 | 81 | 14 | 2 | 12 |
| 15 | Dominique JeffersonQBGoose Creek | 1453 | 111.8 | 6.49 | 224 | 75 | 13 | 6 | 13 |
| 16 | Kenny SmithFB, DEAFHS (Fairfax) | 1324 | 110.3 | 8.43 | 157 | 85 | 17 | 6 | 12 |
| 17 | Quintein AndersonRBSumter | 1277 | 98.2 | 6.87 | 186 | 50 | 23 | 5 | 13 |
| 18 | Anthony SandersRB, DBTHA (Ridgeland) | 1237 | 137.4 | 8.53 | 145 | 42 | 6 | 0 | 9 |
| 19 | TyShawn BainesRB, MLBLake City | 1202 | 120.2 | 5.89 | 204 | 74 | 13 | 0 | 10 |
| 20 | Chad GilchristRB, DEStrom Thurmond (Johnston) | 1200 | 109.1 | 6.32 | 190 | 79 | 11 | 2 | 11 |
| 21 | Dalton SwiresRB, FSFox Creek (North Augusta) | 1183 | 118.3 | 7.94 | 149 | 0 | 14 | 0 | 10 |
| 22 | Josh ValdezFBLake Marion (Santee) | 1159 | 115.9 | 10.54 | 110 | 55 | 6 | 0 | 10 |
| 23 | Travonta WilliamsRB, DBAFHS (Fairfax) | 1154 | 82.4 | 7.96 | 145 | 50 | 9 | 3 | 14 |
| 24 | Dylven CovingtonRB, WRMCHS (Bennettsville) | 1137 | 103.4 | 6.65 | 171 | 48 | 11 | 0 | 11 |
| 25 | Ikeem PoseyCB, RBGaffney | 1137 | 94.8 | 5.49 | 207 | 50 | 7 | 9 | 12 |
| 26 | D'marco JacksonOLB, SSBroome (Spartanburg) | 1134 | 113.4 | 6.16 | 184 | 70 | 8 | 5 | 10 |
| 27 | Tavien FeasterRBSpartanburg | 1121 | 86.2 | 7.23 | 155 | 75 | 10 | 2 | 13 |
| 28 | Robert JamesWR, DBWilson Hall (Sumter) | 1116 | 101.5 | 7.64 | 146 | 87 | 18 | 0 | 11 |
| 29 | Cameron DelanoFB, MLBCWHS (Pickens) | 1115 | 159.3 | 9.45 | 118 | 43 | 9 | 2 | 7 |
| 30 | Evan UleryFBGoose Creek | 1103 | 100.3 | 7.82 | 141 | 49 | 11 | 1 | 11 |
| 31 | Keenan SimpsonRB, FBCane Bay (Summerville) | 1095 | 99.5 | 7.06 | 155 | 95 | 9 | 2 | 11 |
| 32 | James "the flash" davisRBLake Marion (Santee) | 1078 | 107.8 | 8.69 | 124 | 60 | 6 | 0 | 10 |
| 33 | Frankie JohnsonSB, CBDarlington | 1066 | 96.9 | 5.96 | 179 | 54 | 16 | 1 | 11 |
| 34 | Jay UrichQBWren (Piedmont) | 1031 | 85.9 | 5.66 | 182 | 0 | 9 | 3 | 12 |
| 35 | Nathaniel EkwereRBWren (Piedmont) | 1021 | 85.1 | 5.40 | 189 | 0 | 17 | 5 | 12 |
| 36 | Kahleb ParksRB, CBNorth Charleston | 1015 | 112.8 | 7.58 | 134 | 86 | 11 | 0 | 9 |
| 37 | Leandre LegreeFBGoose Creek | 1015 | 92.3 | 7.00 | 145 | 68 | 13 | 0 | 11 |
| 38 | Tyler FoxRB, LBHHP (Hilton Head Island) | 1013 | 84.4 | 10.13 | 100 | 0 | 9 | 0 | 12 |
| 39 | Ali KelleyRBRidge View (Columbia) | 1004 | 91.3 | 8.81 | 114 | 85 | 9 | 2 | 11 |
| 40 | Ronald (rj) RoderickQB, RBCane Bay (Summerville) | 993 | 82.8 | 4.80 | 207 | 62 | 12 | 11 | 12 |
| 41 | Thomas WheelerOLB, RBDarlington | 988 | 89.8 | 7.06 | 140 | 65 | 13 | 2 | 11 |
| 42 | Cyrus ClarkRB, FBARHS (Summerville) | 984 | 89.5 | 5.12 | 192 | 45 | 12 | 1 | 11 |
| 43 | Jerrell Suber-o'nealRBFCHS (Winnsboro) | 980 | 81.7 | 6.32 | 155 | 39 | 5 | 1 | 12 |
| 44 | Darian BarksdaleRB, LBCWHS (Pickens) | 975 | 139.3 | 9.38 | 104 | 67 | 4 | 0 | 7 |
| 45 | Gavin HurlbutRB, OLBHHP (Hilton Head Island) | 970 | 80.8 | 6.69 | 145 | 0 | 12 | 0 | 12 |
| 46 | Christian GaskinsRB, LBCA (Myrtle Beach) | 962 | 137.4 | 6.68 | 144 | 80 | 7 | 0 | 7 |
| 47 | Brett FergusonDE, RBFort Mill | 949 | 79.1 | 5.27 | 180 | 37 | 11 | 1 | 12 |
| 48 | Michael GrimsleyRB, SBSouth Florence (Florence) | 935 | 77.9 | 4.95 | 189 | 14 | 9 | 0 | 12 |
| 49 | Sam WatfordWR, LBWilson Hall (Sumter) | 932 | 84.7 | 7.40 | 126 | 68 | 6 | 0 | 11 |
| 50 | Josh EdwardsQBWade Hampton (Greenville) | 922 | 92.2 | 4.96 | 186 | 73 | 12 | 0 | 10 |
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