| 1 | Mikeal SullivanWRACHS (Martinez) | 42.17 | 253 | 6 | 0 | 8 |
| 2 | Terrance BrownWRBaptist Hill (Hollywood) | 40.33 | 242 | 6 | 70 | 7 |
| 3 | Jaeon AllenRB, CBBattery Creek (Beaufort) | 39.71 | 278 | 7 | 73 | 7 |
| 4 | Des LoringRBWando (Mt. Pleasant) | 39.67 | 357 | 9 | 95 | 7 |
| 5 | Luke WindhamK, PFCHS (Florence) | 38.60 | 193 | 5 | 42 | 9 |
| 6 | Jordan SmithWR, CBRidge View (Columbia) | 38.00 | 266 | 7 | 64 | 6 |
| 7 | Chandler Mccall 2022 wr db fs kr prFS, WRNMBHS (Little River) | 37.60 | 188 | 5 | 99 | 9 |
| 8 | Jesus DowdleLBGaffney | 37.33 | 224 | 6 | 75 | 6 |
| 9 | Hayden HickmanWR, RBDillon Christian (Dillon) | 35.43 | 248 | 7 | 70 | 9 |
| 10 | Clay RebrickRB, SBACHS (Anderson) | 34.62 | 277 | 8 | 89 | 5 |
| 11 | Nazeviah BurrisWRJames F. Byrnes (Duncan) | 34.36 | 378 | 11 | 0 | 4 |
| 12 | Bennett GallowayRBChapin | 34.00 | 612 | 18 | 0 | 8 |
| 13 | Javares HamiltonWRDaniel (Central) | 32.50 | 260 | 8 | 0 | 8 |
| 14 | Djay EaleyWR, CBAndrew Jackson (Kershaw) | 31.20 | 156 | 5 | 79 | 5 |
| 15 | Devron WilliamsLB, RBStrom Thurmond (Johnston) | 29.40 | 147 | 5 | 40 | 5 |
| 16 | Ryan ShirleyWR, CBGCHS (Greenwood) | 28.60 | 143 | 5 | 52 | 9 |
| 17 | Antonio WilliamsWR, QBDutch Fork (Irmo) | 28.25 | 226 | 8 | 57 | 10 |
| 18 | Cale MackRB, OLBGCHS (Greenwood) | 27.43 | 384 | 14 | 75 | 8 |
| 19 | Jerrick FosterCB, WRNation Ford (Fort Mill) | 26.50 | 371 | 14 | 95 | 5 |
| 20 | Jamian RisherRB, CBHCHS (Varnville) | 25.90 | 259 | 10 | 80 | 6 |
| 21 | Gerell WatkinsWRNorthwestern (Rock Hill) | 25.83 | 310 | 12 | 92 | 8 |
| 22 | Tyler BrownWREastside (Taylors) | 25.50 | 306 | 12 | 80 | 6 |
| 23 | Jj HudsonRB, FST.L. Hanna (Anderson) | 25.33 | 228 | 9 | 62 | 8 |
| 24 | Colton CaulderPee Dee Academy (Mullins) | 25.00 | 125 | 5 | 35 | 9 |
| 25 | Tyler BrownWREastside (Taylors) | 24.86 | 348 | 14 | 80 | 7 |
| 26 | Myles MartinRB, WREasley | 24.67 | 148 | 6 | 33 | 8 |
| 27 | Quinton HarrisonCBCrestwood (Sumter) | 24.50 | 147 | 6 | 75 | 6 |
| 28 | Kobe PaysourWRGaffney | 24.14 | 169 | 7 | 51 | 7 |
| 29 | James MurphyCBBEHS (Charleston) | 24.00 | 264 | 11 | 60 | 7 |
| 30 | Coleby SinclairPee Dee Academy (Mullins) | 23.40 | 234 | 10 | 64 | 9 |
| 31 | Leroy Bracey jr.RB, WRCamden | 22.86 | 160 | 7 | 0 | 8 |
| 32 | Bryshaun JonesWRSpartanburg | 22.67 | 272 | 12 | 0 | 6 |
| 33 | Will BarberRB, WRFCHS (Winnsboro) | 22.56 | 203 | 9 | 0 | 5 |
| 34 | Jalil Garvin-MingoRBCNHS (Columbia) | 21.79 | 305 | 14 | 42 | 8 |
| 35 | Caden SullivanFS, SSBSHS (Spartanburg) | 21.31 | 277 | 13 | 51 | 7 |
| 36 | Jaylen BoudreauxRBCane Bay (Summerville) | 21.17 | 127 | 6 | 34 | 8 |
| 37 | Joshua SturgeonFort Mill | 21.05 | 400 | 19 | 31 | 6 |
| 38 | Javonne RichardsonDBStall (Charleston) | 20.86 | 146 | 7 | 0 | 7 |
| 39 | Nick ShippyBroome (Spartanburg) | 20.80 | 104 | 5 | 30 | 6 |
| 40 | Miles CrossWRRock Hill | 20.56 | 185 | 9 | 37 | 6 |
| 41 | Jamal CrawfordCB, FSEasley | 19.84 | 377 | 19 | 46 | 8 |
| 42 | Caleb OakleyCB, WRPee Dee Academy (Mullins) | 19.80 | 99 | 5 | 38 | 9 |
| 43 | Dylan SchaeferWR, CBFort Mill | 19.40 | 97 | 5 | 32 | 5 |
| 44 | Mekhi DurantWR, ATHRock Hill | 19.20 | 96 | 5 | 32 | 5 |
| 45 | Jay StaggsWR, CBSpartanburg | 18.82 | 207 | 11 | 0 | 6 |
| 46 | Kendall NormanWRDorman (Roebuck) | 18.80 | 94 | 5 | 21 | 6 |
| 47 | Chris ClemonsWREasley | 18.50 | 111 | 6 | 27 | 8 |
| 48 | Aziz HuffWR, FSGreenville | 18.20 | 91 | 5 | 0 | 6 |
| 49 | Demontavious DraytonWR, CBAFHS (Fairfax) | 18.20 | 91 | 5 | 9 | 7 |
| 50 | Tyler GeterWRCamden | 18.12 | 145 | 8 | 0 | 7 |
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