| 1 | Qwauntez HarleyFB, MLBAFHS (Fairfax) | 1336 | 167.0 | 10.20 | 131 | 60 | 11 | 0 | 8 |
| 2 | Xaviar GarvinQB, FSEstill | 744 | 124.0 | 9.18 | 81 | 80 | 8 | 0 | 6 |
| 3 | Jamil BobeanRB, WREstill | 465 | 93.0 | 6.20 | 75 | 25 | 5 | 1 | 5 |
| 4 | Derrick SimonsQB, DEBBHS (Orangeburg) | 456 | 45.6 | 6.25 | 73 | 20 | 7 | 0 | 10 |
| 5 | Keith ChisholmCB, WRWhale Branch (Beaufort) | 393 | 39.3 | 8.54 | 46 | 78 | 7 | 1 | 10 |
| 6 | Kamauri KellyRB, CBAFHS (Fairfax) | 349 | 87.2 | 11.63 | 30 | 49 | 2 | 0 | 4 |
| 7 | Mykai VoidRB, DEBBHS (Orangeburg) | 345 | 38.3 | 4.06 | 85 | 20 | 4 | 0 | 9 |
| 8 | Angelo LewisWR, FSEstill | 235 | 39.2 | 7.34 | 32 | 30 | 2 | 0 | 6 |
| 9 | Jakhi PushaWR, QBWhale Branch (Beaufort) | 195 | 19.5 | 3.48 | 56 | 39 | 2 | 7 | 10 |
| 10 | Davon EvansDB, RBWhale Branch (Beaufort) | 193 | 21.4 | 3.71 | 52 | 16 | 2 | 2 | 9 |
| 11 | Terry WrightRB, CBAFHS (Fairfax) | 179 | 44.8 | 7.46 | 24 | 25 | 2 | 0 | 4 |
| 12 | Jharius SandersATH, WRAFHS (Fairfax) | 175 | 58.3 | 9.72 | 18 | 48 | 2 | 0 | 3 |
| 13 | Jayvion HarrisRB, LBWhale Branch (Beaufort) | 154 | 25.7 | 3.50 | 44 | 15 | 2 | 1 | 6 |
| 14 | Jamaris MillerRB, WREstill | 149 | 29.8 | 6.77 | 22 | 24 | 0 | 0 | 5 |
| 15 | Mason GriffinRB, OLBWhale Branch (Beaufort) | 143 | 35.8 | 8.41 | 17 | 43 | 3 | 0 | 4 |
| 16 | Alonzo AllenWhale Branch (Beaufort) | 67 | 6.7 | 2.58 | 26 | 13 | 1 | 0 | 10 |
| 17 | Jercurious BlockerRB, DEWhale Branch (Beaufort) | 60 | 6.7 | 2.31 | 26 | 10 | 0 | 1 | 9 |
| 18 | Jaylon GilyardRB, CBBBHS (Orangeburg) | 54 | 5.4 | 6.75 | 8 | 20 | 0 | 0 | 10 |
| 19 | Mandrell GarvinRB, MLBEstill | 32 | 6.4 | 4.00 | 8 | 9 | 0 | 0 | 5 |
| 20 | Talon LeeWR, DEWhale Branch (Beaufort) | 19 | 2.4 | 4.75 | 4 | 9 | 1 | 1 | 8 |
| 21 | Jaquil MackCB, FSBBHS (Orangeburg) | 19 | 2.7 | 3.80 | 5 | 7 | 0 | 0 | 7 |
| 22 | Kavon ChisolmT, DEEstill | 15 | 2.5 | 3.75 | 4 | 6 | 0 | 0 | 6 |
| 23 | Ja'Darious GarrettDB, WRWhale Branch (Beaufort) | 12 | 1.3 | 4.00 | 3 | 6 | 1 | 0 | 9 |
| 24 | Travon MillerRB, LBBBHS (Orangeburg) | 12 | 2.4 | 2.00 | 6 | 5 | 0 | 0 | 5 |
| 25 | Jahleel StaleyRB, SSBBHS (Orangeburg) | 8 | 1.1 | 1.14 | 7 | 4 | 0 | 0 | 7 |
| 26 | Zamir BrothersLB, RBBBHS (Orangeburg) | 7 | 0.8 | 7.00 | 1 | 0 | 0 | 0 | 9 |
| 27 | Jermon BowersQB, CBWhale Branch (Beaufort) | 6 | 1.2 | 0.24 | 25 | 22 | 1 | 6 | 5 |
