| 1 | Juels I huntleyRB, CBFCHS (Florence) | 1926 | 160.5 | 8.16 | 236 | 71 | 27 | 0 | 12 |
| 2 | Jeremiah SingletonOLB, RBNA (Charleston) | 1343 | 149.2 | 7.99 | 168 | 65 | 23 | 1 | 9 |
| 3 | Dylan JonesWilson Hall (Sumter) | 1327 | 120.6 | 11.74 | 113 | 78 | 19 | 0 | 11 |
| 4 | Grayson SalegoRBPP (Summerville) | 919 | 76.6 | 6.30 | 146 | 74 | 9 | 1 | 12 |
| 5 | Will WatsonQB, FSPP (Summerville) | 872 | 87.2 | 10.02 | 87 | 76 | 10 | 2 | 10 |
| 6 | Dylan ClarkQB, FSHHCA (Hilton Head Island) | 766 | 58.9 | 4.05 | 189 | 48 | 17 | 4 | 13 |
| 7 | Miles Van pattenWilson Hall (Sumter) | 673 | 51.8 | 6.60 | 102 | 67 | 9 | 0 | 13 |
| 8 | Marik GibbsRB, SFBS (Charleston) | 507 | 101.4 | 7.68 | 66 | 51 | 4 | 0 | 5 |
| 9 | Ben ReynoldsWilson Hall (Sumter) | 444 | 34.2 | 7.16 | 62 | 64 | 3 | 0 | 13 |
| 10 | Asa WindhamQB, WRPP (Summerville) | 339 | 28.2 | 7.37 | 46 | 45 | 6 | 2 | 12 |
| 11 | Kaven FordRBNA (Charleston) | 334 | 66.8 | 6.07 | 55 | 80 | 5 | 0 | 5 |
| 12 | Jack BurnettWR, CBPP (Summerville) | 310 | 31.0 | 7.21 | 43 | 54 | 3 | 0 | 10 |
| 13 | Colby RichardsonPee Dee Academy (Mullins) | 308 | 30.8 | 3.80 | 81 | 22 | 2 | 2 | 10 |
| 14 | Josh DavisSS, RBFCHS (Florence) | 293 | 29.3 | 4.37 | 67 | 43 | 2 | 1 | 10 |
| 15 | Clark KinneyQBWilson Hall (Sumter) | 255 | 23.2 | 3.31 | 77 | 45 | 10 | 0 | 11 |
| 16 | James CrosbyQB, DEHHCA (Hilton Head Island) | 253 | 19.5 | 3.51 | 72 | 21 | 1 | 0 | 13 |
| 17 | Tristan HeckmanPee Dee Academy (Mullins) | 244 | 24.4 | 3.75 | 65 | 22 | 7 | 1 | 10 |
| 18 | Miles TrussellPee Dee Academy (Mullins) | 188 | 17.1 | 6.96 | 27 | 95 | 5 | 2 | 11 |
| 19 | Zacobi Riley #11QBFBS (Charleston) | 169 | 33.8 | 4.12 | 41 | 9 | 2 | 1 | 5 |
| 20 | Cody WallaceRB, DLFCHS (Florence) | 162 | 16.2 | 4.91 | 33 | 32 | 1 | 0 | 10 |
| 21 | Andrew MillerRB, OLBFCHS (Florence) | 152 | 13.8 | 6.33 | 24 | 76 | 2 | 1 | 11 |
| 22 | Tyshon MansellWR, CBHHCA (Hilton Head Island) | 149 | 13.5 | 8.76 | 17 | 41 | 3 | 0 | 11 |
| 23 | Dawson AndersonDL, FBFCHS (Florence) | 132 | 12.0 | 3.47 | 38 | 20 | 0 | 0 | 11 |
| 24 | Harris NaylorWRWilson Hall (Sumter) | 130 | 11.8 | 10.00 | 13 | 60 | 1 | 0 | 11 |
| 25 | Jackson BonserWilson Hall (Sumter) | 123 | 9.5 | 12.30 | 10 | 80 | 1 | 0 | 13 |
| 26 | Will BassPee Dee Academy (Mullins) | 114 | 11.4 | 3.17 | 36 | 17 | 1 | 0 | 10 |
| 27 | Slate LewisPee Dee Academy (Mullins) | 112 | 10.2 | 3.29 | 34 | 22 | 2 | 0 | 11 |
| 28 | Milling GallowayRBWilson Hall (Sumter) | 111 | 9.2 | 4.44 | 25 | 15 | 0 | 0 | 12 |
| 29 | Landon FeaginQB, WRFCHS (Florence) | 103 | 9.4 | 4.29 | 24 | 15 | 3 | 2 | 11 |
| 30 | J.t. KingRB, DEPP (Summerville) | 101 | 8.4 | 5.61 | 18 | 16 | 2 | 2 | 12 |
| 31 | Kres LanghalsQBHHCA (Hilton Head Island) | 100 | 16.7 | 4.17 | 24 | 13 | 1 | 2 | 6 |
| 32 | Gavin HoltQBFCHS (Florence) | 98 | 8.9 | 3.27 | 30 | 26 | 1 | 0 | 11 |
| 33 | Jameson BerryTE, MLBFCHS (Florence) | 97 | 8.1 | 6.93 | 14 | 42 | 1 | 1 | 12 |
| 34 | Blake VanpattenWR, CBWilson Hall (Sumter) | 73 | 5.6 | 7.30 | 10 | 35 | 1 | 0 | 13 |
| 35 | Zane WilsonRB, MLBHHCA (Hilton Head Island) | 68 | 5.2 | 5.23 | 13 | 14 | 1 | 1 | 13 |
| 36 | Luke PedersonWilson Hall (Sumter) | 48 | 3.7 | 5.33 | 9 | 17 | 0 | 0 | 13 |
| 37 | Ben MclaurinRBWilson Hall (Sumter) | 36 | 3.3 | 4.50 | 8 | 12 | 0 | 0 | 11 |
| 38 | Reid MccollumWR, QBHHCA (Hilton Head Island) | 36 | 2.8 | 1.38 | 26 | 20 | 1 | 0 | 13 |
| 39 | Daniel WigginsCB, WRPP (Summerville) | 33 | 2.8 | 5.50 | 6 | 16 | 0 | 0 | 12 |
| 40 | Antwaun HendersonWR, CBNA (Charleston) | 29 | 2.6 | 14.50 | 2 | 16 | 0 | 0 | 11 |
| 41 | Hughes ElvingtonPee Dee Academy (Mullins) | 20 | 1.8 | 2.86 | 7 | 9 | 0 | 0 | 11 |
| 42 | London JohnsonPee Dee Academy (Mullins) | 19 | 1.9 | 3.80 | 5 | 11 | 0 | 0 | 10 |
| 43 | Brooks PostonWR, CBFCHS (Florence) | 19 | 1.6 | 3.80 | 5 | 10 | 0 | 0 | 12 |
| 44 | Austin JohnsonFCHS (Florence) | 15 | 1.7 | 5.00 | 3 | 5 | 0 | 0 | 9 |
| 45 | Gabriel CookRB, LSNA (Charleston) | 13 | 1.3 | 2.60 | 5 | 10 | 1 | 0 | 10 |
| 46 | Landon CoatesRB, DBFCHS (Florence) | 6 | 1.5 | 3.00 | 2 | 4 | 0 | 0 | 4 |
| 47 | Jacob FloydPee Dee Academy (Mullins) | 4 | 0.4 | 2.00 | 2 | 3 | 0 | 0 | 10 |
| 48 | Ryan SmallPee Dee Academy (Mullins) | 3 | 0.6 | 3.00 | 1 | 3 | 0 | 0 | 5 |
| 49 | Drew WolfeQB, WRNA (Charleston) | 2 | 0.5 | 2.00 | 1 | 2 | 0 | 0 | 4 |
| 50 | O'maury MckelveyPee Dee Academy (Mullins) | 2 | 0.2 | 2.00 | 1 | 2 | 0 | 0 | 11 |
