| 1 | Kamron McGillDE, MLBAndrew Jackson (Kershaw) | 122 | 12.2 | 93 | 29 | 3.0 | 3.0 | 10 |
| 2 | Jase FairOLBAndrew Jackson (Kershaw) | 122 | 12.2 | 93 | 29 | 0 | 0 | 10 |
| 3 | Samson PetersLB, TEAMHS (North Charleston) | 104 | 11.6 | 0 | 0 | 8.0 | 3.0 | 9 |
| 4 | BJ ASHFORDRB, LBEau Claire (Columbia) | 102 | 10.2 | 102 | 0 | 11.0 | 1.0 | 10 |
| 5 | Sincere HubbardMLB, FBChesterfield | 97 | 9.7 | 22 | 75 | 3.0 | 0.0 | 10 |
| 6 | Andre LittlejohnRB, LBMullins | 96 | 10.7 | 42 | 54 | 22.0 | 0 | 9 |
| 7 | Sam HunterBuford (Lancaster) | 87 | 10.9 | 36 | 51 | 5.0 | 0 | 8 |
| 8 | Zechariah JamisonRB, MLBEdisto (Cordova) | 86 | 10.8 | 22 | 64 | 5.0 | 0 | 8 |
| 9 | Nathan PerackiLBMullins | 85 | 9.4 | 31 | 54 | 12.0 | 0 | 9 |
| 10 | Andrew NorthcuttMLB, TEPelion | 85 | 8.5 | 16 | 69 | 3.0 | 0.5 | 10 |
| 11 | Brady CottinghamMLBPelion | 82 | 8.2 | 15 | 67 | 5.0 | 2.0 | 10 |
| 12 | Darriyarn BaxleyWB, LBChester | 81 | 8.1 | 63 | 18 | 10.0 | 2.0 | 10 |
| 13 | Rondrecus PetersonLB, RBColumbia | 81 | 8.1 | 63 | 18 | 20.0 | 1.0 | 10 |
| 14 | Nate ElseyLBPSHS (Charleston) | 80 | 8.0 | 34 | 46 | 10.0 | 1.0 | 10 |
| 15 | Terry RadfordDL, TEChester | 80 | 8.0 | 44 | 36 | 20.0 | 9.0 | 10 |
| 16 | Ethan ChisumPSHS (Charleston) | 78 | 7.8 | 26 | 52 | 10.0 | 4.0 | 10 |
| 17 | Malik TerryMLBHCHS (Varnville) | 76 | 7.6 | 48 | 28 | 10.0 | 0 | 10 |
| 18 | Josiah CastilloMLB, FBColumbia | 76 | 7.6 | 54 | 22 | 6.0 | 0 | 10 |
| 19 | TAVARAS SEIBLESOL, LBEau Claire (Columbia) | 74 | 7.4 | 70 | 0 | 14.0 | 6.0 | 10 |
| 20 | Nick CarterDT, GAndrew Jackson (Kershaw) | 72 | 7.2 | 42 | 30 | 5.0 | 5.0 | 10 |
| 21 | Garrett SmithLB, FBACA (Conway) | 72 | 7.2 | 30 | 42 | 2.0 | 0.0 | 10 |
| 22 | Braylon HarleyLB, RBAndrew Jackson (Kershaw) | 70 | 7.0 | 55 | 15 | 1.0 | 1.0 | 10 |
| 23 | Az SimmonsRB, HBClinton | 69 | 6.9 | 63 | 6 | 6.0 | 2.0 | 10 |
| 24 | Johnny RoseLB, RBAMHS (North Charleston) | 69 | 6.9 | 0 | 0 | 1.0 | 0 | 10 |
| 25 | Bryston ColemanMLB, SSStrom Thurmond (Johnston) | 69 | 6.9 | 37 | 32 | 11.0 | 5.0 | 10 |
| 26 | Jakari HollomanLB, RBCentral (Pageland) | 67 | 8.4 | 33 | 34 | 14.0 | 4.0 | 8 |
| 27 | Diavante IrvingDE, DEPSHS (Charleston) | 66 | 6.6 | 33 | 33 | 11.0 | 3.0 | 10 |
| 28 | JAVION JENKINSRB, LBTimberland (St. Stephen) | 64 | 7.1 | 8 | 0 | 9.0 | 4.0 | 9 |
| 29 | Gavin PoliteOLB, RBHCHS (Varnville) | 62 | 6.9 | 36 | 26 | 14.0 | 2.0 | 9 |
| 30 | Marques AllenRBCentral (Pageland) | 62 | 6.9 | 23 | 39 | 8.0 | 2.0 | 9 |
| 31 | Semaj WilsonQB, MLBACA (Conway) | 62 | 6.2 | 31 | 31 | 2.0 | 0.0 | 10 |
| 32 | Anthony StrongDL, OLCheraw | 62 | 6.2 | 32 | 30 | 15.0 | 4.0 | 10 |
| 33 | Kaylin CulpFS, RBFCHS (Winnsboro) | 61 | 6.8 | 33 | 28 | 10.0 | 2.0 | 9 |
| 34 | Jayden GlennTE, HBClinton | 61 | 6.1 | 55 | 6 | 9.0 | 1.0 | 10 |
| 35 | Braydon BlakeLBHCHS (Varnville) | 60 | 7.5 | 32 | 28 | 1.0 | 0 | 8 |
| 36 | Dre WalkerWR, SSFCHS (Winnsboro) | 60 | 6.0 | 26 | 34 | 7.0 | 1.0 | 10 |
| 37 | Jamari SmallsMLBWhale Branch (Beaufort) | 59 | 6.6 | 53 | 6 | 3.0 | 1.0 | 9 |
| 38 | Wytrayvious DugarStrom Thurmond (Johnston) | 59 | 5.9 | 33 | 26 | 4.0 | 0.0 | 10 |
| 39 | Demaurice JamesDBCheraw | 58 | 6.4 | 36 | 22 | 2.0 | 1.0 | 9 |
| 40 | Ajavian JamesRB, LBClinton | 58 | 5.8 | 53 | 5 | 2.0 | 0 | 10 |
| 41 | Tyler DavisSB, FSHCHS (Varnville) | 58 | 5.8 | 35 | 23 | 6.0 | 0 | 10 |
| 42 | Myles McDuffieFS, TEColumbia | 58 | 5.8 | 43 | 15 | 4.0 | 0 | 10 |
| 43 | Caleb ParrishLB, RBAMHS (North Charleston) | 57 | 6.3 | 0 | 0 | 7.0 | 3.0 | 9 |
| 44 | ANTHONY PEEPLESTE, LBTimberland (St. Stephen) | 57 | 6.3 | 8 | 0 | 1.0 | 0 | 9 |
| 45 | Layson StocktonMLB, TEPSHS (Charleston) | 57 | 5.7 | 16 | 41 | 4.0 | 2.0 | 10 |
| 46 | Jantzen JeffersDE, HBAndrew Jackson (Kershaw) | 57 | 5.7 | 36 | 21 | 7.0 | 5.0 | 10 |
| 47 | Tj JacksonFS, WRPelion | 56 | 5.6 | 26 | 30 | 1.0 | 0 | 10 |
| 48 | Chris BoydWR, FSClinton | 54 | 10.8 | 52 | 2 | 3.0 | 1.0 | 5 |
| 49 | Austin AdamsLBCheraw | 54 | 6.8 | 29 | 25 | 1.0 | 1.0 | 8 |
| 50 | Jaydan WallaceT, DEChesterfield | 54 | 6.0 | 9 | 45 | 3.0 | 2.0 | 9 |