| 1 | Camron MaciejewskiHot Springs | 1741 | 158.3 | 11.16 | 156 | 70 | 28 | 1 | 11 |
| 2 | Trey MaalandQB, DBDeuel (Clear Lake) | 1183 | 118.3 | 6.29 | 188 | 60 | 19 | 0 | 10 |
| 3 | Sam KooimaQB, CBLead-Deadwood (Lead) | 1006 | 143.7 | 6.37 | 158 | 80 | 8 | 2 | 7 |
| 4 | Avery LigonACHS (Aberdeen) | 991 | 99.1 | 5.03 | 197 | 82 | 4 | 1 | 10 |
| 5 | Braden PetersonQB, WRHot Springs | 957 | 87.0 | 11.53 | 83 | 81 | 15 | 0 | 11 |
| 6 | Boden SchilllerRB, OLBSioux Valley (Volga) | 955 | 95.5 | 10.38 | 92 | 83 | 17 | 3 | 10 |
| 7 | Donovan 2 RoseRB, SBSioux Valley (Volga) | 953 | 95.3 | 10.14 | 94 | 83 | 15 | 0 | 10 |
| 8 | Cashton CaudellHuron | 872 | 87.2 | 5.93 | 147 | 62 | 4 | 0 | 10 |
| 9 | Braylon MarshallRB, LBRCCHS (Rapid City) | 817 | 74.3 | 5.45 | 150 | 53 | 8 | 2 | 11 |
| 10 | Cruz SoulekQB, PChamberlain | 790 | 112.9 | 6.08 | 130 | 61 | 6 | 1 | 7 |
| 11 | Colby KoldaRB, LBMHHHS (CO-OP) (Miller) | 691 | 86.4 | 6.78 | 102 | 97 | 4 | 0 | 8 |
| 12 | Simon KiefferQB, DBRCCHS (Rapid City) | 595 | 54.1 | 5.83 | 102 | 38 | 5 | 5 | 11 |
| 13 | Ryder BaileyRB, OLBCuster | 577 | 72.1 | 5.89 | 98 | 38 | 9 | 4 | 8 |
| 14 | Brock ChristophersonRB, MLBSioux Valley (Volga) | 523 | 52.3 | 9.87 | 53 | 56 | 5 | 0 | 10 |
| 15 | Brody WeineisterDE, TERoncalli (Aberdeen) | 466 | 66.6 | 7.52 | 62 | 85 | 6 | 1 | 7 |
| 16 | Gavin KloosRB, LBDeuel (Clear Lake) | 456 | 45.6 | 4.75 | 96 | 27 | 4 | 0 | 10 |
| 17 | Aiden FisherWB, FSRoncalli (Aberdeen) | 429 | 42.9 | 4.42 | 97 | 36 | 0 | 1 | 10 |
| 18 | Ben BrooksQB, DBMadison | 418 | 69.7 | 4.40 | 95 | 61 | 3 | 3 | 6 |
| 19 | Owen HaasRB, LBDeuel (Clear Lake) | 362 | 36.2 | 3.85 | 94 | 16 | 0 | 3 | 10 |
| 20 | Macklen WeberQB, CBBEEHS (CO-OP) (Emery) | 359 | 119.7 | 6.41 | 56 | 46 | 6 | 0 | 3 |
| 21 | Mack SaxonMPHS (Mobridge) | 333 | 66.6 | 4.90 | 68 | 37 | 2 | 1 | 5 |
| 22 | Tyrel SeamanRB, OLLead-Deadwood (Lead) | 302 | 37.8 | 4.19 | 72 | 35 | 2 | 1 | 8 |
| 23 | Drake GustafsonWR, SSBEEHS (CO-OP) (Emery) | 289 | 41.3 | 3.70 | 78 | 36 | 8 | 1 | 7 |
| 24 | Bryce ReuerRB, LBChamberlain | 275 | 39.3 | 4.66 | 59 | 18 | 3 | 1 | 7 |
| 25 | Kaden LarsonTB, CBRoncalli (Aberdeen) | 272 | 27.2 | 3.36 | 81 | 27 | 1 | 1 | 10 |
| 26 | Caleb MurphyRB, OLBSioux Valley (Volga) | 253 | 25.3 | 5.75 | 44 | 49 | 1 | 0 | 10 |
| 27 | Zane BackousQB, MLBRoncalli (Aberdeen) | 247 | 35.3 | 4.33 | 57 | 34 | 4 | 3 | 7 |
| 28 | Austin EricksonFB, RBACHS (Aberdeen) | 231 | 33.0 | 4.62 | 50 | 38 | 3 | 1 | 7 |
| 29 | Colin IversonQB, MLBHot Springs | 220 | 20.0 | 3.19 | 69 | 15 | 6 | 0 | 11 |
| 30 | Garrett MertensQB, FSMilbank | 219 | 43.8 | 4.29 | 51 | 65 | 2 | 1 | 5 |
| 31 | Ethan SteeleRB, LBLakota Tech (Pine Ridge) | 216 | 30.9 | 2.96 | 73 | 50 | 1 | 1 | 7 |
| 32 | Tyrin ScottRB, OLBCuster | 204 | 29.1 | 4.00 | 51 | 40 | 1 | 2 | 7 |
| 33 | Daniel ImmorminoRB, CBCuster | 198 | 24.8 | 5.08 | 39 | 54 | 2 | 2 | 8 |
| 34 | Jordan PedersenOLB, RBMadison | 181 | 18.1 | 3.12 | 58 | 13 | 1 | 2 | 10 |
| 35 | Kean StevensonRB, MLBBEEHS (CO-OP) (Emery) | 175 | 25.0 | 3.98 | 44 | 13 | 0 | 0 | 7 |
| 36 | Riley CaseyQB, DBLakota Tech (Pine Ridge) | 173 | 21.6 | 3.68 | 47 | 27 | 0 | 5 | 8 |
| 37 | Simon FriedRB, CBMPHS (Mobridge) | 165 | 33.0 | 4.71 | 35 | 22 | 0 | 0 | 5 |
| 38 | Colton McneilHuron | 152 | 16.9 | 3.80 | 40 | 11 | 2 | 1 | 9 |
| 39 | Casen TibbettsRB, LBDouglas (Box Elder) | 140 | 46.7 | 3.89 | 36 | 48 | 0 | 0 | 3 |
| 40 | Eli BargerSS, MLBMadison | 140 | 14.0 | 2.98 | 47 | 11 | 1 | 2 | 10 |
| 41 | Jackson EisemannQB, WRMPHS (Mobridge) | 118 | 23.6 | 3.28 | 36 | 36 | 2 | 2 | 5 |
| 42 | Caleb HodgesMadison | 115 | 11.5 | 3.19 | 36 | 14 | 1 | 2 | 10 |
| 43 | Thackary HansonHuron | 109 | 15.6 | 3.89 | 28 | 0 | 1 | 0 | 7 |
| 44 | Julian ToncheRB, DBLakota Tech (Pine Ridge) | 106 | 21.2 | 5.30 | 20 | 20 | 0 | 2 | 5 |
| 45 | Carson JohnsonQB, OLBBEEHS (CO-OP) (Emery) | 101 | 14.4 | 2.52 | 40 | 50 | 2 | 0 | 7 |
| 46 | Riley SchultzRB, LBBaltic | 96 | 32.0 | 8.00 | 12 | 40 | 0 | 0 | 3 |
| 47 | Carson MarkoRB, LBDeuel (Clear Lake) | 88 | 8.8 | 8.80 | 10 | 36 | 3 | 1 | 10 |
| 48 | Corban HannemanQB, RBLennox | 81 | 27.0 | 11.57 | 7 | 10 | 0 | 0 | 3 |
| 49 | Hunter KunzHot Springs | 68 | 11.3 | 17.00 | 4 | 0 | 2 | 0 | 6 |
| 50 | Landon HulstHuron | 65 | 10.8 | 5.91 | 11 | 0 | 2 | 0 | 6 |
