| 1 | Dustin LotzerQB, LBSisseton | 3143 | 392.9 | 2542 | 601 | 10 | 8 |
| 2 | Ryan HanderQBLincoln (Sioux Falls) | 2545 | 195.8 | 2329 | 216 | 0 | 13 |
| 3 | Gannon MooreFB, DELincoln (Sioux Falls) | 1947 | 149.8 | 37 | 1910 | 255 | 13 |
| 4 | Brett GrevlosQBWashington (Sioux Falls) | 1822 | 202.4 | 1505 | 317 | 0 | 9 |
| 5 | Austin SumnerQBBrandon Valley (Brandon) | 1707 | 284.5 | 1707 | 0 | 0 | 6 |
| 6 | Austin KochQB, DBBon Homme (Tyndall) | 1629 | 203.6 | 594 | 1035 | 24 | 8 |
| 7 | Eric DockenQB, DBBeresford | 1351 | 225.2 | 850 | 501 | 0 | 6 |
| 8 | Braden GardnerWinner | 1310 | 109.2 | 0 | 1310 | 400 | 12 |
| 9 | John FarnerWinner | 1105 | 92.1 | 888 | 217 | 0 | 12 |
| 10 | Levi LoudenburgRB, DBHoward | 1012 | 126.5 | 0 | 1012 | 80 | 8 |
| 11 | Austin IversonRB, LBSCHS (Fort Pierre) | 950 | 105.6 | 122 | 828 | 0 | 9 |
| 12 | Andrew EidemTB, LBVermillion | 945 | 105.0 | 0 | 945 | 0 | 9 |
| 13 | Cade HearnenQB, DBMMCHS (CO-OP) (Mitchell) | 930 | 93.0 | 600 | 330 | 0 | 10 |
| 14 | Mason WinterboerWR, LBBrookings | 925 | 154.2 | 0 | 925 | 108 | 6 |
| 15 | Brayden CarlsonQB, DBBrookings | 888 | 148.0 | 898 | -10 | 0 | 6 |
| 16 | Canku One StarQB, DBTodd County (Mission) | 791 | 98.9 | 585 | 206 | 9 | 8 |
| 17 | Alex LoesRB, LBMMCHS (CO-OP) (Mitchell) | 775 | 77.5 | 0 | 775 | 54 | 10 |
| 18 | Jesus DuranRB, LBTodd County (Mission) | 745 | 82.8 | 4 | 741 | 0 | 9 |
| 19 | Wyatt WalterQB, LBHoward | 688 | 86.0 | 525 | 163 | 0 | 8 |
| 20 | Chance ClasonRB, DBHill City | 641 | 80.1 | 0 | 641 | 99 | 8 |
| 21 | Mike OberleFB, LBVermillion | 616 | 61.6 | 0 | 616 | 0 | 10 |
| 22 | Eric SchuethWinner | 604 | 50.3 | 0 | 604 | 75 | 12 |
| 23 | Andrew AugspurgerQB, DBMiller | 582 | 72.8 | 461 | 121 | 0 | 8 |
| 24 | Earl KiertznerQB, DBVermillion | 582 | 58.2 | 523 | 59 | 0 | 10 |
| 25 | Colton McLaughlinQB, DBHill City | 580 | 72.5 | 567 | 13 | 0 | 8 |
| 26 | Kevin BergRB, LBDell Rapids | 564 | 94.0 | 0 | 564 | 13 | 6 |
| 27 | Kyle McKelveyRB, LBBeresford | 560 | 93.3 | 0 | 560 | 171 | 6 |
| 28 | Tyler ReimanRB, DBSCHS (Fort Pierre) | 544 | 60.4 | 0 | 544 | 236 | 9 |
| 29 | Jordan KondaQB, DLLennox | 543 | 108.6 | 339 | 204 | 0 | 5 |
| 30 | Cody EricksonQB, DBBritton-Hecla (Britton) | 535 | 133.8 | 454 | 81 | 0 | 4 |
| 31 | Preston HarrisRB, LBHarrisburg | 526 | 87.7 | 0 | 526 | 0 | 6 |
| 32 | Tate BunkersRB, LBDell Rapids | 525 | 87.5 | 0 | 525 | 21 | 6 |
| 33 | Jacob DawsonRB, DLHoward | 525 | 65.6 | 0 | 525 | 38 | 8 |
| 34 | Trevor FarmerRB, DBTodd County (Mission) | 521 | 57.9 | 10 | 511 | 204 | 9 |
| 35 | Sam HoskinsRBWashington (Sioux Falls) | 508 | 84.7 | 0 | 508 | 28 | 6 |
| 36 | Graham SchuetzleRB, SSPTFR (Pierre) | 492 | 123.0 | 254 | 238 | 47 | 4 |
| 37 | Adam McNamaraQB, DBHarrisburg | 481 | 80.2 | 188 | 293 | 0 | 6 |
| 38 | Matt EngelmannRB, LBMiller | 465 | 58.1 | 0 | 465 | 214 | 8 |
| 39 | Joey OlsonQB, DBSturgis Brown (Sturgis) | 451 | 75.2 | 477 | -26 | 0 | 6 |
| 40 | Tad SchuurmansRB, DBBon Homme (Tyndall) | 417 | 59.6 | 15 | 402 | 69 | 7 |
| 41 | Dan NoonanRB, LBHoward | 416 | 52.0 | 0 | 416 | 52 | 8 |
| 42 | Tyler ChristensenRB, LBSioux Valley (Volga) | 386 | 48.2 | 0 | 386 | 100 | 8 |
| 43 | Ryan ToelleQB, DBSisseton | 379 | 63.2 | 257 | 122 | 0 | 6 |
| 44 | Cody SkilesRB, LBHill City | 379 | 47.4 | 0 | 379 | 76 | 8 |
| 45 | Alex SchultzQBLincoln (Sioux Falls) | 358 | 27.5 | 348 | 10 | 0 | 13 |
| 46 | Josh RogersQB, DBSCHS (Fort Pierre) | 356 | 39.6 | 242 | 114 | 0 | 9 |
| 47 | Preston DavisQB, DBDell Rapids | 350 | 58.3 | 350 | 0 | 0 | 6 |
| 48 | Cedric WilliamsRB, DBMiller | 347 | 43.4 | 0 | 347 | 20 | 8 |
| 49 | Grant RennerRB, LBBritton-Hecla (Britton) | 346 | 86.5 | 0 | 346 | 69 | 4 |
| 50 | Clint WilsonRB, LBSturgis Brown (Sturgis) | 345 | 57.5 | 0 | 345 | 83 | 6 |