| 1 | Vontrez RushRB, DBSimmons (Hollandale) | 280 | 23.3 | 39 | 0 | 0 | 0 | 12 |
| 2 | Dayan BilboRBVancleave | 246 | 22.4 | 41 | 0 | 0 | 0 | 11 |
| 3 | Deriaun TownsendRB, SBWinona | 184 | 18.4 | 30 | 0 | 0 | 0 | 10 |
| 4 | Dante DowdellRB, DEPicayune | 168 | 11.2 | 28 | 0 | 0 | 0 | 15 |
| 5 | Ja'karius GrantRBWLHS (Collinsville) | 162 | 13.5 | 25 | 0 | 0 | 0 | 12 |
| 6 | Mason HorneK, FBClarkdale (Meridian) | 156 | 15.6 | 19 | 2 | 32 | 0 | 10 |
| 7 | Aaron SteeleATHKemper County (DeKalb) | 151 | 11.6 | 23 | 0 | 3 | 0 | 13 |
| 8 | Jay StevensonDL, RBEupora | 144 | 13.1 | 24 | 0 | 0 | 0 | 11 |
| 9 | Robert JenningsDE, RBMorton | 144 | 12.0 | 20 | 0 | 0 | 0 | 12 |
| 10 | Drey LenoirRBD'Iberville | 144 | 12.0 | 24 | 0 | 0 | 0 | 12 |
| 11 | Jalen WashingtonRB, SSHouston | 138 | 15.3 | 22 | 0 | 0 | 0 | 9 |
| 12 | Tyrick JonesRB, OLBBay Springs | 136 | 13.6 | 18 | 0 | 0 | 0 | 10 |
| 13 | Trevon BrownRB, DBSDHS (Rolling Fork) | 134 | 12.2 | 20 | 0 | 0 | 0 | 11 |
| 14 | Dee RushQB, LBSimmons (Hollandale) | 134 | 11.2 | 17 | 0 | 0 | 0 | 12 |
| 15 | Carter CockrellRB, DBSA (Mendenhall) | 134 | 11.2 | 22 | 0 | 0 | 0 | 12 |
| 16 | Jamari ThompsonRBPearl | 132 | 11.0 | 22 | 0 | 0 | 0 | 12 |
| 17 | Bray HubbardCB, QBOcean Springs | 132 | 11.0 | 22 | 0 | 0 | 0 | 12 |
| 18 | K'swaya Moffett jr.RB, CBRaymond | 130 | 11.8 | 21 | 0 | 0 | 0 | 11 |
| 19 | Deandre Smith, jr.QBGCHS (Greenville) | 126 | 12.6 | 20 | 0 | 0 | 0 | 10 |
| 20 | Jordan FranksP, CBMooreville | 126 | 12.6 | 20 | 0 | 0 | 0 | 10 |
| 21 | Robert Dumas, jrRBMadison Central (Madison) | 126 | 11.5 | 21 | 0 | 0 | 0 | 11 |
| 22 | Omar JohnsonRB, OLBColumbia | 126 | 10.5 | 21 | 0 | 0 | 0 | 12 |
| 23 | Dicenzo Miller iiATHKemper County (DeKalb) | 124 | 10.3 | 20 | 0 | 0 | 0 | 12 |
| 24 | Suntarine PerkinsRB, SSRaleigh | 122 | 10.2 | 18 | 0 | 8 | 0 | 12 |
| 25 | Jeremiah DillionWR, CBTylertown | 118 | 9.8 | 19 | 0 | 0 | 0 | 12 |
| 26 | Red ParkerQB, FSHouston | 116 | 12.9 | 19 | 0 | 0 | 0 | 9 |
| 27 | Noah CutterRB, OLBBay (Bay St. Louis) | 116 | 9.7 | 19 | 0 | 0 | 0 | 12 |
| 28 | Cobey CraftTaylorsville | 114 | 10.4 | 19 | 0 | 0 | 0 | 11 |
| 29 | Jarvis DurrSS, RBBrandon | 114 | 8.1 | 19 | 0 | 0 | 0 | 14 |
| 30 | Jacob ScottWRMooreville | 112 | 11.2 | 18 | 0 | 0 | 0 | 10 |
| 31 | Terrance MackQB, RBVelma Jackson (Camden) | 112 | 11.2 | 17 | 0 | 2 | 0 | 10 |
| 32 | Makarious MichaelsDE, TESebastopol | 112 | 9.3 | 18 | 0 | 0 | 0 | 12 |
| 33 | Jermarius LewisATHNorth Pike (Summit) | 108 | 10.8 | 18 | 0 | 0 | 0 | 10 |
| 34 | Larry SimmonsWRMoss Point | 108 | 9.8 | 16 | 0 | 0 | 0 | 11 |
| 35 | Chris DavisRB, CBPicayune | 108 | 7.2 | 18 | 0 | 0 | 0 | 15 |
| 36 | Reece WolfeQB, FSOFA (Amite) | 106 | 10.6 | 17 | 0 | 0 | 0 | 10 |
| 37 | Nate Blount ivRBBrandon | 106 | 9.6 | 17 | 0 | 0 | 0 | 11 |
| 38 | Omarion BlakesATH, QBShaw | 106 | 8.8 | 16 | 0 | 0 | 0 | 12 |
| 39 | Donavin GreenATHYazoo County (Yazoo City) | 104 | 11.6 | 17 | 0 | 0 | 0 | 9 |
| 40 | Omar ScottRB, LBWA (Louisville) | 104 | 10.4 | 17 | 0 | 0 | 0 | 10 |
| 41 | Zee SimsWR, CBEnterprise | 104 | 9.5 | 17 | 0 | 0 | 0 | 11 |
| 42 | Christopher BellWRGCHS (Greenville) | 102 | 12.8 | 16 | 0 | 0 | 0 | 8 |
| 43 | Tyler ReedRBGulfport | 102 | 10.2 | 17 | 0 | 0 | 0 | 10 |
| 44 | Emmanual RandelRB, CBTCP (Belden) | 102 | 9.3 | 17 | 0 | 0 | 0 | 11 |
| 45 | Ja’naylon DupreeWRNCHS (Philadelphia) | 102 | 7.8 | 17 | 0 | 0 | 0 | 13 |
| 46 | Josh SykesWRPPCA (Pearl) | 100 | 10.0 | 15 | 0 | 0 | 1 | 10 |
| 47 | Kye NelsonTB, OLBSt. Joseph (Greenville) | 100 | 10.0 | 15 | 0 | 0 | 0 | 10 |
| 48 | Dabyron ConerlyLB, WRLumberton | 100 | 9.1 | 16 | 0 | 0 | 0 | 11 |
| 49 | Kris GinnFB, LBCA (Columbia) | 100 | 8.3 | 16 | 0 | 0 | 0 | 12 |
| 50 | Dandreyus GilesDB, WRHCCHS (Lexington) | 98 | 12.2 | 13 | 0 | 0 | 0 | 8 |
